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Nancy G. Weiland
Researcher at Rockefeller University
Publications - 44
Citations - 4482
Nancy G. Weiland is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hypothalamus & Receptor. The author has an hindex of 29, co-authored 44 publications receiving 4401 citations. Previous affiliations of Nancy G. Weiland include University of Maryland, Baltimore.
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Estradiol increases the sensitivity of hippocampal CA1 pyramidal cells to NMDA receptor-mediated synaptic input: correlation with dendritic spine density.
TL;DR: Estradiol treatment increases sensitivity of CA1 pyramidal cells to NMDA receptor-mediated synaptic input; further, sensitivity to NMda receptor- mediated synaptic input is well correlated with dendritic spine density.
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Ovarian steroids and the brain: Implications for cognition and aging
TL;DR: Three effects of estrogens and progestins that are especially relevant to memory processes are discussed and hormonal alterations associated with aging and neurodegenerative diseases are identified.
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Differential Regulation of NMDAR1 mRNA and Protein by Estradiol in the Rat Hippocampus
TL;DR: The data suggest that estradiol modulates NMDA receptor function via post-transcriptional regulation of the NMDAR1 subunit protein, which could account for estrogen-induced changes in pharmacological and physiological properties of the NMDA receptors.
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Distribution and hormone regulation of estrogen receptor immunoreactive cells in the hippocampus of male and female rats
TL;DR: Estrogen regulates the synaptic plasticity and physiology of the hippocampus as well as learning behaviors that are mediated by the hippocampus and can have a direct effect on hippocampal neurons and that any sex differences in estrogen responsiveness is due to something other than sex Differences in ER levels or function in the hippocampus.
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Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus
TL;DR: Data indicate that the agonist and antagonist binding sites on the NMDA receptor/ion channel complex are regulated independently by an as yet unidentified mechanism, and that this regulation exhibits regional specificity in the hippocampus.