N
Nandul Durfa
Researcher at Federal Ministry of Health
Publications - 8
Citations - 590
Nandul Durfa is an academic researcher from Federal Ministry of Health. The author has contributed to research in topics: Antivenom & Echis ocellatus. The author has an hindex of 7, co-authored 8 publications receiving 503 citations.
Papers
More filters
Journal ArticleDOI
Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches.
Daniel Petras,Daniel Petras,Libia Sanz,Álvaro Segura,María Herrera,Mauren Villalta,Daniela Solano,Mariángela Vargas,Guillermo León,David A. Warrell,R. David G. Theakston,Robert A. Harrison,Nandul Durfa,Abdulsalam Nasidi,José María Gutiérrez,Juan J. Calvete +15 more
TL;DR: The ability of EchiTAb-Plus-ICP antivenom to immunodeplete and neutralize the venoms of African spitting cobras was assessed by antivenomics and neutralization tests and the lack of neutralization of lethality of N. nubiae venom may be of medical relevance only in relatively populous areas of the Saharan region.
Journal ArticleDOI
Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria.
Isa S. Abubakar,Saidu B. Abubakar,Abdulrazaq G. Habib,Abdulsalam Nasidi,Nandul Durfa,Peter Ofemile Yusuf,Solomon Larnyang,John Garnvwa,Elijah N Sokomba,L.A. Salako,R. David G. Theakston,Ed Juszczak,Nicola Alder,David A. Warrell +13 more
TL;DR: At these doses, ET-Plus was slightly more effective but ET-G was slightly safer, and both are recommended for treating E. ocellatus envenoming in Nigeria.
Journal ArticleDOI
Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom.
Nicholas R. Casewell,Darren A. N. Cook,Simon C. Wagstaff,Abdulsalami Nasidi,Nandul Durfa,Wolfgang Wüster,Robert A. Harrison +6 more
TL;DR: It is demonstrated that the new anti-E.
Journal ArticleDOI
Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa.
Álvaro Segura,Mauren Villalta,María Herrera,Guillermo León,Robert A. Harrison,Nandul Durfa,Abdusalami Nasidi,Juan J. Calvete,R. David G. Theakston,David A. Warrell,David A. Warrell,José María Gutiérrez +11 more
TL;DR: It is concluded that EchiTAb-Plus-ICP has a good preclinical neutralizing profile against homologous and heterologous viperid venoms from other sub-Saharan African locations and constitutes a promising therapeutic option for the treatment of snakebite envenoming in this region.
Journal ArticleDOI
Pre-clinical and preliminary dose-finding and safety studies to identify candidate antivenoms for treatment of envenoming by saw-scaled or carpet vipers (Echis ocellatus) in northern Nigeria.
Saidu B. Abubakar,Isa S. Abubakar,Abdulrazaq G. Habib,A. Nasidi,Nandul Durfa,Peter Ofemile Yusuf,S. Larnyang,J. Garnvwa,Elijah N Sokomba,L.A. Salako,Gavin D. Laing,R.D.G. Theakston,Edmund Juszczak,Nicola Alder,David A. Warrell +14 more
TL;DR: The aim of this study was to identify candidate antivenom with specific activity against the venom of the saw-scaled or carpet viper in northern Nigeria, where bites by this species cause great morbidity and mortality but where effective antivenoms have become scarce and unaffordable.