N
Nanette H. Bishopric
Researcher at University of Miami
Publications - 111
Citations - 7752
Nanette H. Bishopric is an academic researcher from University of Miami. The author has contributed to research in topics: Myocyte & Apoptosis. The author has an hindex of 44, co-authored 109 publications receiving 7371 citations. Previous affiliations of Nanette H. Bishopric include United States Department of Veterans Affairs & University of California, San Francisco.
Papers
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Journal ArticleDOI
Expression of Lewy body protein septin 4 in postmortem brain of Parkinson's disease and control subjects.
Lina A. Shehadeh,Lina A. Shehadeh,Georgia Mitsi,Nikhil Adi,Nanette H. Bishopric,Spyridon Papapetropoulos +5 more
TL;DR: Similar signal expression patterns and parallel accumulation of SEPT4 and α‐synuclein in well‐characterized postmortem PD brain are presented for the first time.
Journal ArticleDOI
Fusigenic Liposome-mediated DNA Transfer into Cardiac Myocytes
Kristin E. Ellison,Nanette H. Bishopric,Nanette H. Bishopric,Keith A. Webster,Ryuichi Morishita,Gary H. Gibbons,Yasufumi Kaneda,Barbara Sato,Victor J. Dzau +8 more
TL;DR: HVJ/liposome-mediated transfer is efficient for the transfection of both oligonucleotides and plasmids into cardiac myocytes both in vitro and in vivo, and may provide a new tool for the investigation of cardiac myocyte biology and disease.
Journal ArticleDOI
Reversal of pathological cardiac hypertrophy via the MEF2-coregulator interface.
Jianqin Wei,Shaurya Joshi,Svetlana Speransky,Christopher Crowley,Nimanthi Jayathilaka,Xiao Lei,Yongqing Wu,David Gai,Sumit Jain,Michael Hoosien,Yan Gao,Lin Chen,Nanette H. Bishopric +12 more
TL;DR: It is concluded thatMEF2 acetylation is required for development and maintenance of pathological cardiac hypertrophy, and that blocking MEF2acetylation can permit recovery from hypertrotrophy without impairing physiologic adaptation.
Journal ArticleDOI
Acidosis Regulates the Stability, Hydrophobicity, and Activity of the BH3-Only Protein Bnip3
Donna P. Frazier,Amber Wilson,Regina M. Graham,John W. Thompson,Nanette H. Bishopric,Keith A. Webster +5 more
TL;DR: It is reported that acidic pH mediates increased half-lives of Bnip3 dimers and monomers as well as that of a faster-migrating fragment (>10-) and confers protection against degradation by protease and demonstrates a pH-sensitive shift in the stability and apparent hydrophobicity of BNip3 monomers that correlates closely with membrane binding and function.
Patent
Tissue specific hypoxia regulated therapeutic constructs
Keith A. Webster,Nanette H. Bishopric,Brian J. Murphy,Keith R. Laderoute,Christopher J. Green +4 more
TL;DR: Methods and compositions relating to chimeric genes containing a tissue-specific promoter and a hypoxia response enhancer element, both of which are operably linked to a selected gene, such as a reporter gene, therapeutic gene (e.g., bcl-2, NOS, catalase and SOD), or deleterious gene are disclosed.