N
Nanette H. Bishopric
Researcher at University of Miami
Publications - 111
Citations - 7752
Nanette H. Bishopric is an academic researcher from University of Miami. The author has contributed to research in topics: Myocyte & Apoptosis. The author has an hindex of 44, co-authored 109 publications receiving 7371 citations. Previous affiliations of Nanette H. Bishopric include United States Department of Veterans Affairs & University of California, San Francisco.
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Journal ArticleDOI
Introducing JACC: Basic to Translational Science: Why Now?
Douglas L. Mann,Brian H. Annex,Nanette H. Bishopric,Thomas Force,Daniel P. Kelly,Peter Libby,Robert Roberts,Eva van Rooij,Gordon F. Tomaselli,L. Kristin Newby +9 more
TL;DR: The Editors are pleased to present the inaugural edition of JACC: Basic to Translational Science, which questions the need for a journal dedicated to bringing the fruits of fundamental science to translational science.
Journal ArticleDOI
Negative lusitropy and abnormal calcium handling in hypoxic cardiac myocytes exposed to the calcium-sensitizer EMD 53998.
TL;DR: The results indicate that increased calcium sensitivity results in marked impairment of relaxation under hypoxic conditions, possibly due to the impaired calcium sequestration and increased calcium availability exhibited by hypoxic myocytes.
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Dysfunctional potassium channel subunit interaction as a novel mechanism of long QT syndrome.
Michael Hoosien,Mary Ellen Ahearn,Robert J. Myerburg,Thai V. Pham,Todd Miller,Marcel J.D. Smets,Lisa Baumbach-Reardon,Ming-Lon Young,Amjad Farooq,Nanette H. Bishopric +9 more
TL;DR: The structural model shows that this mutation effectively immobilizes voltage gating by an inhibitory interaction that is additive with that of KCNE1, illuminating a previously unreported mechanism for LQTS, and validate recent theoretical models of the closed state of the KCNQ1:KCNE1 complex.
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Angiotensin II receptor subtype AT1 and AT2 expression after heart transplantation.
Lars Gullestad,Guy A. Haywood,Halfdan Aass,Heather Ross,Gail Yee,Thor Ueland,Odd Geiran,John Kjekshus,Svein Simonsen,Nanette H. Bishopric,Michael B. Fowler +10 more
TL;DR: rary to expectations, mRNA for both Ang II receptors was downregulated after heart transplantation, but the hypertrophy does not appear to be driven by increased transcription of the AT1 receptor.
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Expression of α‐synuclein mRNA in Parkinson's disease
TL;DR: The observation is consistent with the hypothesis that an increase in SNCA expression may be a contributory factor, among other factors, to the development of at least some cases of sporadic PD.