Nasim Ebrahimi

TL;DR: Different types of oncolytic viruses, their application in clinical trials, and finally challenges faced by the field of on colytic virotherapy and strategies to overcome them are discussed.

TL;DR: In this paper, Adenovirus vectors have been used for different purposes, including as oncolytic agents to kill cancer cells, carrier for RNA interference to block oncoproteins expression, vaccines for eliciting immune responses, especially in cytotoxic T lymphocytes (CTLs), and gene therapy vehicles for restoring p53 and Rb function.

TL;DR: Neoantigens are cancer cell-specific antigens which their expression leads to the immune stimulation against tumor cells as mentioned in this paper, which can induce anti-tumor T-cell responses to destroy tumors without damaging healthy cells.

TL;DR: In this article, a review highlights the differences between regular cancer cells and CSC metabolism and discusses the action mechanisms of energy disruptors at the cellular and molecular levels and highlights the difference between CSCs and normal cells.

TL;DR: In this article, the analysis, visualization, and modeling of high-dimensional data, with a focus on single-cell technologies, sequence, and structure analysis, are discussed. But, despite considerable investment in basic science, improvements in technology, and increased knowledge of the biology of human disease, translation of laboratory findings into substantial therapeutic progress has been slower than expected.