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Michael R. Hamblin

Researcher at University of Johannesburg

Publications -  1017
Citations -  77670

Michael R. Hamblin is an academic researcher from University of Johannesburg. The author has contributed to research in topics: Medicine & Photodynamic therapy. The author has an hindex of 117, co-authored 899 publications receiving 59533 citations. Previous affiliations of Michael R. Hamblin include Semmelweis University & The Royal Marsden NHS Foundation Trust.

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Photodynamic therapy and anti-tumour immunity

TL;DR: Photodynamic therapy uses non-toxic photosensitizers and harmless visible light in combination with oxygen to produce cytotoxic reactive oxygen species that kill malignant cells by apoptosis and/or necrosis, shut down the tumour microvasculature and stimulate the host immune system.
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Photodynamic therapy: a new antimicrobial approach to infectious disease?

TL;DR: All the available evidence suggests that multi-antibiotic resistant strains are as easily killed by PDT as naive strains, and that bacteria will not readily develop resistance to PDT.
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Mechanisms in photodynamic therapy: part one—-photosensitizers, photochemistry and cellular localization

TL;DR: The most important factor governing the outcome of PDT is how the PS interacts with cells in the target tissue or tumor, and the key aspect of this interaction is the subcellular localization of the PS.