Natasha Costa da Rocha Galucio

TL;DR: Evaluated the genotoxicity and mutagenicity of isoeleutherin and eleutherin using a bioassay on Allium cepa and micronuclei and performed an in silico evaluation of the toxic potential of these molecules using the PreADMET server to assess whether binding to TOPO II influences toxicity.

TL;DR: In this paper, the authors measured cucurbitacin in different Luffa operculata extracts, evaluating the antiproliferative and genotoxic activity of the extracts and the isolated substance in gastric cancer cells line, and evaluating the possible mechanism of action.

TL;DR: This study accomplished the botanical and phytochemical characterization, antimicrobial activity and cytotoxic of E. bulbosa, finding that the less citotoxicity of EE is related to the presence of anthocyanins that are present on bulbs epidermis.

TL;DR: In this article, the authors evaluated the cytotoxicity, genotoxicity and oral toxicity of the ethanol extract (EEEp), dichloromethane fraction (FDMEp) of E. plicata, and isoeleutherin.

TL;DR: This estudo objetivou avaliar, por meio da literatura, a forma correta de uso do metilfenidato, o uso indiscriminado, off label and os problemas de saúde that o usos prolongado pode desencadear no usuário, assim como a importância da atenção farmacêutica for um tratamento eficaz