N
Nathalie Parizel
Researcher at Centre national de la recherche scientifique
Publications - 4
Citations - 517
Nathalie Parizel is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Oligodendrocyte & Myelin. The author has an hindex of 4, co-authored 4 publications receiving 484 citations.
Papers
More filters
Journal ArticleDOI
Brain dysmyelination and recovery assessment by noninvasive in vivo diffusion tensor magnetic resonance imaging.
Laura A. Harsan,Patrick Poulet,Blandine Guignard,Jérôme Steibel,Nathalie Parizel,Paulo Loureiro de Sousa,Nelly Boehm,Daniel Grucker,M. Said Ghandour +8 more
TL;DR: It is shown clearly that myelination and axonal changes play a role in the degree of diffusion anisotropy, because FA was significantly decreased in dysmyelinated brain.
Journal ArticleDOI
Recovery from Chronic Demyelination by Thyroid Hormone Therapy: Myelinogenesis Induction and Assessment by Diffusion Tensor Magnetic Resonance Imaging
Laura A. Harsan,Jérôme Steibel,Anita Zaremba,Arnaud Agin,Rémy Sapin,Patrick Poulet,Blandine Guignard,Nathalie Parizel,Daniel Grucker,Nelly Boehm,Robert H. Miller,M. Said Ghandour +11 more
TL;DR: Injection of triiodothyronine (T3) hormone over a 3 week interval after cuprizone withdrawal progressively restored the normal DT-MRI phenotype accompanied by an improvement of clinical signs and remyelination, establishing a role for T3 as an inducer of oligodendrocyte progenitor cells in adult mouse brain following chronic demyelinations.
Journal ArticleDOI
Astrocytic hypertrophy in dysmyelination influences the diffusion anisotropy of white matter
Laura A. Harsan,Patrick Poulet,Blandine Guignard,Nathalie Parizel,Robert P. Skoff,M. Said Ghandour +5 more
TL;DR: The amplified magnitude of radial and axial diffusions in jimpy males was attributed principally to the strongly pronounced astrocyte hypertrophy, and major changes of DT‐MRI parameters in the two dysmyelinated mice caused by the myelin loss and axonal modifications were highlighted.
Journal ArticleDOI
Fast measurement of relaxation times by steady‐state free precession of 129Xe in carrier agents for hyperpolarized noble gases
TL;DR: Optized gas transport can be achieved through controlled T1 and T2 measurements of 129Xe gas at equilibrium, using the steady‐state free precession method (SSFP), which was proven with the use of CuSO4‐doped water samples and xenon dissolved in chloroform.