Nelly Boehm

TL;DR: It is shown clearly that myelination and axonal changes play a role in the degree of diffusion anisotropy, because FA was significantly decreased in dysmyelinated brain.

TL;DR: Injection of triiodothyronine (T3) hormone over a 3 week interval after cuprizone withdrawal progressively restored the normal DT-MRI phenotype accompanied by an improvement of clinical signs and remyelination, establishing a role for T3 as an inducer of oligodendrocyte progenitor cells in adult mouse brain following chronic demyelinations.

TL;DR: It is demonstrated that testosterone treatment efficiently stimulates the formation of new myelin and reverses myelin damage in chronic demyelinated brain lesions, resulting from the long-term administration of cuprizone, which is toxic for oligodendrocytes.

TL;DR: The information in this study comprises a new layer of detail in the understanding of the action of cationic helical antimicrobial peptides and shows that rational design is capable of producing potentially therapeutic membrane active peptides with properties tailored to their function.

TL;DR: It is suggested that surgical intervention should be considered for patients presenting in a similar manner, perhaps at an earlier stage than when ulcerated, as previously recommended.