N
Neng Wang
Researcher at Guangzhou University of Chinese Medicine
Publications - 38
Citations - 2469
Neng Wang is an academic researcher from Guangzhou University of Chinese Medicine. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 24, co-authored 38 publications receiving 1778 citations. Previous affiliations of Neng Wang include Peking Union Medical College & Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Journal ArticleDOI
MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin
Zhiyu Wang,Neng Wang,Pengxi Liu,Qianjun Chen,Honglin Situ,Ting Xie,Jianxing Zhang,Cheng Peng,Yi-Xing Lin,Jianping Chen +9 more
TL;DR: Results indicate that ISL acts as a natural autophagy inducer to increase breast cancer chemosensitivity, but also reveal that miR-25 functions as a novel regulator of autophagic cell death by targeting ULK1.
Journal ArticleDOI
A review: The pharmacology of isoliquiritigenin
Fu Peng,Fu Peng,Qiaohui Du,Cheng Peng,Neng Wang,Hailin Tang,Hailin Tang,Xiaoming Xie,Jiangang Shen,Jianping Chen,Jianping Chen +10 more
TL;DR: This review aims at providing a comprehensive summary of the pharmacological activities of ISL from a number of reliable sources including PubMed, ScienceDirect, Springer, and Wiley‐Blackwell.
Journal ArticleDOI
Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer
Neng Wang,Zhiyu Wang,Sui-Lin Mo,Tjing Yung Loo,Dongmei Wang,Hai Bin Luo,Depo Yang,Yuling Chen,Jiangang Shen,Jianping Chen +9 more
TL;DR: Ellagic acid significantly inhibited a series of VEGF-induced angiogenesis processes including proliferation, migration, and tube formation of endothelial cells and directly inhibited VEGFR-2 tyrosine kinase activity and its downstream signaling pathways including MAPK and PI3K/Akt in endothelial Cells.
Journal ArticleDOI
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Neng Wang,Weiping Liu,Yifeng Zheng,Shengqi Wang,Bowen Yang,Min Li,Ju-Xian Song,Ju-Xian Song,Fengxue Zhang,Xiaotong Zhang,Qi Wang,Zhiyu Wang +11 more
TL;DR: Bioinformatic analysis and clinical investigation suggested that high CXCL1 expression is significantly correlated with breast cancer lymph node metastasis, poor overall survival and basal-like subtype, and CxCL1-based therapy might become a novel strategy for breast cancer metastasis prevention.
Journal ArticleDOI
Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway
Zhiyu Wang,Neng Wang,Shouwei Han,Dongmei Wang,Sui-Lin Mo,Linzhong Yu,Hui Huang,Kamchuen Tsui,Jiangang Shen,Jianping Chen +9 more
TL;DR: This study found that ISL significantly inhibited the VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs) at non-toxic concentration and shed light on the potential application of ISL as a novel natural inhibitor for cancer angiogenesis via the V EGF/VEGFR-2 pathway.