Q
Qi Wang
Researcher at Guangzhou University of Chinese Medicine
Publications - 295
Citations - 5203
Qi Wang is an academic researcher from Guangzhou University of Chinese Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 27, co-authored 253 publications receiving 2983 citations. Previous affiliations of Qi Wang include Guangzhou University.
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Journal ArticleDOI
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Neng Wang,Weiping Liu,Yifeng Zheng,Shengqi Wang,Bowen Yang,Min Li,Ju-Xian Song,Ju-Xian Song,Fengxue Zhang,Xiaotong Zhang,Qi Wang,Zhiyu Wang +11 more
TL;DR: Bioinformatic analysis and clinical investigation suggested that high CXCL1 expression is significantly correlated with breast cancer lymph node metastasis, poor overall survival and basal-like subtype, and CxCL1-based therapy might become a novel strategy for breast cancer metastasis prevention.
Journal ArticleDOI
In silico polypharmacology of natural products.
TL;DR: The promise of cancer immunotherapies and combination therapies that target tumor ecosystems (e.g. clones or 'selfish' sub-clones) via exploiting the immunological and inflammatory 'side' effects of natural products in the cancer post-genomics era is highlighted.
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Deep Learning-Based Prediction of Drug-Induced Cardiotoxicity.
Chuipu Cai,Pengfei Guo,Yadi Zhou,Jingwei Zhou,Qi Wang,Fengxue Zhang,Jiansong Fang,Feixiong Cheng,Feixiong Cheng,Feixiong Cheng +9 more
TL;DR: A powerful deep learning-based tool for risk assessment of hERG-mediated cardiotoxicities in drug discovery and postmarketing surveillance is presented and several novel predicted hERG blockers on approved antineoplastic agents are showcased.
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Metformin attenuates hyperalgesia and allodynia in rats with painful diabetic neuropathy induced by streptozotocin.
TL;DR: Investigation in diabetic rats found that metformin is able to attenuate diabetes-induced hyperalgesia and allodynia, which might be associated its anti-oxidative effect through AMPK pathway, and might be used as an effective drug for abnormal sensation in painful diabetic neuropathy.
Journal ArticleDOI
(-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression.
Xiang Chang,Cuiping Rong,Yun-Bo Chen,Cong Yang,Qian Hu,Yousheng Mo,Chun-Xia Zhang,Xiaoqiong Gu,Lei Zhang,Wen-Qing He,Shuyi Cheng,Xue-Qin Hou,Ru-yu Su,Sijun Liu,Wenjun Dun,Qi Wang,Shuhuan Fang +16 more
TL;DR: It is demonstrated that EGCG reduced β-amyloid accumulation in vitro and rescued cognitive deterioration in senescence-accelerated mice P8 (SAMP8) via intragastric administration of low- and high-dose E GCG (5 and 15 mg/kg, respectively) for 60 days.