N
Nicholas Bastidas
Researcher at New York University
Publications - 54
Citations - 3802
Nicholas Bastidas is an academic researcher from New York University. The author has contributed to research in topics: Medicine & Cranial vault. The author has an hindex of 14, co-authored 39 publications receiving 3520 citations. Previous affiliations of Nicholas Bastidas include Hofstra University & Hospital of the University of Pennsylvania.
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Journal ArticleDOI
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
Daniel J. Ceradini,Anita R Kulkarni,Matthew J. Callaghan,Oren M. Tepper,Nicholas Bastidas,Mark E. Kleinman,Jennifer M. Capla,Robert D. Galiano,Jamie P. Levine,Geoffrey C. Gurtner +9 more
TL;DR: It is shown that SDF-1 gene expression is regulated by the transcription factor hypoxia-inducible factor-1 (HIF-1) in endothelial cells, resulting in selective in vivo expression of S DF-1 in ischemic tissue in direct proportion to reduced oxygen tension.
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Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells.
Robert D. Galiano,Oren M. Tepper,Catherine R. Pelo,Kirit A. Bhatt,Matthew J. Callaghan,Nicholas Bastidas,Stuart Bunting,Hope Steinmetz,Geoffrey C. Gurtner +8 more
TL;DR: Topical VEGF is able to improve wound healing by locally up-regulating growth factors important for tissue repair and by systemically mobilizing bone marrow-derived cells, including a population that contributes to blood vessel formation, and recruiting these cells to the local wound environment where they are able to accelerate repair.
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Mechanical strain alters gene expression in an in vitro model of hypertrophic scarring.
Christopher A. Derderian,Nicholas Bastidas,Oren Z. Lerman,Kirit A. Bhatt,Shin E. Lin,Jeremy Voss,Jeffrey W. Holmes,Jamie P. Levine,Geoffrey C. Gurtner,Geoffrey C. Gurtner +9 more
TL;DR: Results suggest that mechanical strain up-regulates matrix remodeling genes and down-regulate normal cellular apoptosis, resulting in more cells, each of which produces more matrix, which may underlie the pathophysiology of hypertrophic scars and other fibrotic processes in vivo.
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Uniaxial Mechanical Strain : An In Vitro Correlate to Distraction Osteogenesis
Kirit A. Bhatt,Eric I. Chang,Stephen M. Warren,Shin-e Lin,Nicholas Bastidas,Shadi Ghali,Aurelia Thibboneir,Jennifer M. Capla,Joseph G. McCarthy,Geoffrey C. Gurtner +9 more
TL;DR: Uniaxial cyclic strain using the Flexcell device under appropriate strain parameters provides a novel in vitro model that induces osteoblast cellular and molecular expression patterns that simulate patterns observed in the in vivo distraction gap.
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Posterior cranial vault expansion using distraction osteogenesis
TL;DR: Posterior cranial vault distraction offers several benefits over traditional expansion procedures, and the several advantages, diverse utility, and technicalities of the operative procedure are highlighted.