N
Nicholas Gaddum
Researcher at King's College London
Publications - 35
Citations - 1045
Nicholas Gaddum is an academic researcher from King's College London. The author has contributed to research in topics: Pulse wave velocity & Preload. The author has an hindex of 16, co-authored 34 publications receiving 910 citations. Previous affiliations of Nicholas Gaddum include University of Queensland & University of New South Wales.
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Journal ArticleDOI
Bisphosphonate-Anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-Circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) Imaging
Lydia Sandiford,Alkystis Phinikaridou,Andrea Protti,Levente K. Meszaros,Xianjin Cui,Yong Yan,George Frodsham,Peter Williamson,Nicholas Gaddum,René M. Botnar,Philip J. Blower,Mark Green,Rafael Torres Martin de Rosales +12 more
TL;DR: A new stealth PEG polymer conjugate containing a terminal 1,1-bisphosphonate (BP) group for strong and stable binding to the surface of ultrasmall-superparamagnetic oxide nanomaterials (USPIOs) is prepared, demonstrating the potential of PEG(5)-BP-USPios for the development of targeted multimodal imaging agents for molecular imaging.
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A technical assessment of pulse wave velocity algorithms applied to non-invasive arterial waveforms.
TL;DR: This work studied the effects of measurement noise, temporal resolution and similarity of the two waveforms used for PWV calculation upon accuracy and variability and proposed the following criteria to identify the most accurate and least variable algorithm.
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Theoretical foundations of a Starling-like controller for rotary blood pumps.
Robert F. Salamonsen,Robert F. Salamonsen,Einly Lim,Nicholas Gaddum,Abdul-Hakeem H. Alomari,Shaun D. Gregory,Shaun D. Gregory,Michael C. Stevens,David Glen Mason,John F. Fraser,Daniel Timms,Mohan Karunanithi,Nigel H. Lovell +12 more
TL;DR: Pump flow pulsatility showed more correspondence with changes in LV stroke work before and after opening of the aortic valve and was least affected by changes in the LV and right ventricular (RV) contractility, blood volume, peripheral vascular resistance, and heart rate.
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Three-dimensional atrial wall thickness maps to inform catheter ablation procedures for atrial fibrillation.
Martin J. Bishop,Ronak Rajani,Gernot Plank,Nicholas Gaddum,Gerry Carr-White,Matthew Wright,Mark D O'Neill,Steven A. Niederer +7 more
TL;DR: Left atrial wall thickness can be measured robustly and efficiently across the wholeleft atrium using a solution of the Laplace equation over a finite element mesh of the left atrium.
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Biventricular assist devices: a technical review.
TL;DR: The BiVAD systems potentially offer an improved quality of life to patients with total heart failure, and thus a viable alternative to heart transplantation is anticipated with continued development.