N
Nicholas W. Pino
Researcher at University of Illinois at Urbana–Champaign
Publications - 4
Citations - 120
Nicholas W. Pino is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Progenitor cell & Aldehyde dehydrogenase. The author has an hindex of 3, co-authored 4 publications receiving 62 citations.
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Journal ArticleDOI
NitroxylFluor: A Thiol-Based Fluorescent Probe for Live-Cell Imaging of Nitroxyl
TL;DR: A new thiol-based HNO-responsive trigger that can compete against reactive thiols for HNO is reported that capitalizes on two established physical organic phenomena; the alpha-effect and the Thorpe-Ingold effect and developed NitroxylFluor, a selective H NO-responsive fluorescent probe.
Journal ArticleDOI
Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1
Chelsea Anorma,Jamila Hedhli,Thomas E. Bearrood,Nicholas W. Pino,Sarah H. Gardner,Hiroshi Inaba,Pamela Zhang,Yanfen Li,Daven Feng,Sara E. Dibrell,Kristopher A. Kilian,Kristopher A. Kilian,Lawrence W. Dobrucki,Timothy M. Fan,Jefferson Y. Chan +14 more
TL;DR: AlDeSense, a turn-on fluorescent probe for aldehyde dehydrogenase 1A1 (ALDH1A1) and Ctrl-AlDe Sense, a matching nonresponsive reagent are presented and it is demonstrated that cells exhibiting high AlDeSense signal intensity have properties of CSCs.
Journal ArticleDOI
A Photoactivatable Formaldehyde Donor with Fluorescence Monitoring Reveals Threshold To Arrest Cell Migration
Lukas P. Smaga,Nicholas W. Pino,Gabriela E. Ibarra,Vishnu V. Krishnamurthy,Jefferson Y. Chan +4 more
TL;DR: Application of photoFAD-3 uncovered the concentration range necessary for arresting wound healing in live cells and marks the first report where a photoactivatable donor for any analyte has been used to quantify intracellular release.
Journal ArticleDOI
Thienylpiperidine Donor NIR Xanthene-Based Dye for Photoacoustic Imaging.
Chathuranga S. L. Rathnamalala,Nicholas W. Pino,Bailey S. Herring,Mattea Hooper,Steven R. Gwaltney,Jefferson Y. Chan,Colleen N. Scott +6 more
TL;DR: XanthCR-880 as mentioned in this paper is a xanthene-based near-infrared (NIR) photoacoustic (PA) dyes with absorbance > 800 nm.