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Nicolas Duhem

Researcher at Université catholique de Louvain

Publications -  8
Citations -  1026

Nicolas Duhem is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Micelle & Nanocarriers. The author has an hindex of 7, co-authored 8 publications receiving 915 citations.

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Book ChapterDOI

Chitosan and chitosan derivatives in drug delivery and tissue engineering

Raphaël Riva, +5 more
TL;DR: This review aims to provide an overview of chitosan and chitOSan derivatives used for drug delivery, with a special emphasis on chemical modifications of ch itosan to achieve specific biomedical purpose.
Journal ArticleDOI

Fate of polymeric nanocarriers for oral drug delivery

Laurence Plapied, +3 more
- 01 Jun 2011 - 
TL;DR: This review will focus on two polymeric nanocarriers: nanoparticles and micelles that have been studied for oral drug delivery at preclinical level and their mechanisms of uptake and their fate after oral delivery will be discussed.
Journal ArticleDOI

Vitamin E-based nanomedicines for anti-cancer drug delivery

Nicolas Duhem, +2 more
- 28 May 2014 - 
TL;DR: This review aims to highlight the development of novel vitamin E conjugates for the vectorization of active pharmaceutical ingredients through nanotechnologies, and describes the biology and the metabolic functions of vitamin E.
Journal ArticleDOI

Self-Assembling Doxorubicin−Tocopherol Succinate Prodrug as a New Drug Delivery System: Synthesis, Characterization, and in Vitro and in Vivo Anticancer Activity

Nicolas Duhem, +10 more
- 15 Jan 2014 - 
TL;DR: In vivo, in vitro biological assessment showed significant anticancer activity and temperature-dependent cellular uptake of N-DOX-TOS nanoparticles, which showed a greater antitumor efficacy than free DOX.
Journal ArticleDOI

Tocol modified glycol chitosan for the oral delivery of poorly soluble drugs.

Nicolas Duhem, +7 more
- 28 Feb 2012 - 
TL;DR: Tocopherol succinate glycol chitosan (GC-TOS) conjugates spontaneously formed micelles in aqueous solution with a critical micelle concentration of 2 μg mL −1 and may be promising vehicles for the oral delivery of poorly soluble drugs.