Journal ArticleDOI
Vitamin E-based nanomedicines for anti-cancer drug delivery
TLDR
This review aims to highlight the development of novel vitamin E conjugates for the vectorization of active pharmaceutical ingredients through nanotechnologies, and describes the biology and the metabolic functions of vitamin E.About:
This article is published in Journal of Controlled Release.The article was published on 2014-05-28. It has received 211 citations till now. The article focuses on the topics: Drug delivery & Vitamin E.read more
Citations
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Review of Natural Compounds for Potential Skin Cancer Treatment
Tawona N. Chinembiri,Lissinda H. Du Plessis,Minja Gerber,Josias H. Hamman,Jeanetta du Plessis +4 more
TL;DR: This review aims at providing an overview of anti-cancer compounds, derived from natural sources, that are currently used in cancer chemotherapies, or that have been reported to show anti-melanoma, or anti-skin cancer activities.
Journal ArticleDOI
A review of drug release mechanisms from nanocarrier systems
Chizhu Ding,Zibiao Li +1 more
TL;DR: Various nano-delivery systems consisting of different covalent linkages to conjugate the therapeutic molecules as well as those that carry the unmodified drug molecules by encapsulating or complexation are summarized, including ester, amide/peptide, disulfide, hydrazone, hypoxia-activated and self-immolative linkages.
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Microfluidic Synthesis of Rigid Nanovesicles for Hydrophilic Reagents Delivery
TL;DR: Hollow-structured rigid nanovesicle that co-encapsulate siRNA and doxorubicin (Dox) reveals a significantly enhanced anti-tumor effect for a multi-drug resistant tumor model.
Journal ArticleDOI
Vitamin E: Regulatory Redox Interactions
TL;DR: The relationship between vitamin E and redox interactions with absorption, distribution, metabolism, and excretion of vitamin E, oxidative stress and ROS in the body, and recent recognition of the field of oxidative stress research are introduced.
Journal ArticleDOI
Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy.
Hira Choudhury,Bapi Gorain,Manisha Pandey,Santosh Ashok Kumbhar,Rakesh K. Tekade,Arun K. Iyer,Prashant Kesharwani +6 more
TL;DR: It could be concluded that TPGS based nanoparticulate application is an advanced approach to improve therapeutic efficacy of chemotherapeutic agents by better internalization and sustained retention of the NPs.
References
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Nanoparticle therapeutics: an emerging treatment modality for cancer
TL;DR: The features of nanoparticle therapeutics that distinguish them from previous anticancer therapies are highlighted, and how these features provide the potential for therapeutic effects that are not achievable with other modalities are described.
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Strategies in the design of nanoparticles for therapeutic applications
TL;DR: This Review focuses on recent progress important for the rational design of such nanoparticles and discusses the challenges to realizing the potential of nanoparticles.
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Biodegradable polymeric nanoparticles based drug delivery systems
TL;DR: The impact of nanoencapsulation of various disease related drugs on biodegradable nanoparticles such as PLGA, PLA, chitosan, gelatin, polycaprolactone and poly-alkyl-cyanoacrylates is highlighted.
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Impact of Nanotechnology on Drug Delivery
TL;DR: This work focuses on the application of nanotechnology to drug delivery and highlights several areas of opportunity where current and emerging nanotechnologies could enable entirely novel classes of therapeutics.
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Delivering nanomedicine to solid tumors
TL;DR: In this paper, the authors review the barriers to the delivery of cancer therapeutics and summarize strategies that have been developed to overcome these barriers and discuss design considerations for optimizing the nanoparticles to tumors.