N
Nicolas Masurier
Researcher at University of Montpellier
Publications - 58
Citations - 666
Nicolas Masurier is an academic researcher from University of Montpellier. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 15, co-authored 47 publications receiving 557 citations. Previous affiliations of Nicolas Masurier include Centre national de la recherche scientifique & University of Rouen.
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Journal ArticleDOI
Helical Oligomers of Thiazole-Based γ-Amino Acids: Synthesis and Structural Studies†
Loïc Mathieu,Baptiste Legrand,Cheng Deng,Lubomir Vezenkov,Emmanuel Wenger,Claude Didierjean,Muriel Amblard,Marie-Christine Averlant-Petit,Nicolas Masurier,Vincent Lisowski,Jean Martinez,Ludovic T. Maillard +11 more
TL;DR: 9-Helix: 4-Amino(methyl)-1,3-thiazole-5-carboxylic acids (ATCs) were synthesized as new γ-amino acid building blocks and adopted a well-defined 9-helix structure in the solid state and in aprotic and protic organic solvents as well as in aqueous solution.
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Novel imidazo[1,2-a]naphthyridinic systems (part 1): synthesis, antiproliferative and DNA-intercalating activities.
Mounir Andaloussi,Emmanuel Moreau,Nicolas Masurier,Jacques Lacroix,René C.-Gaudreault,Jean-Michel Chezal,Anas El Laghdach,Damien Canitrot,Eric Debiton,Jean-Claude Teulade,Olivier Chavignon +10 more
TL;DR: Pentacyclic derivatives 13b and 14a exhibited in vitro activity comparable to anticancer agent such as amsacrine, and a direct intercalation of the drugs into DNA by electrophoresis on agarose gel was highlighted.
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Synthesis of 2-substituted β-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon
Nicolas Masurier,François Estour,Marie-Thérèse Froment,Bertrand Lefèvre,Jean-Claude Debouzy,Bernard Brasme,Patrick Masson,Olivier Lafont +7 more
TL;DR: Beta-cyclodextrin was substituted by an iodosobenzoic acid derivative to create a catalytic hydrolytic activity against neurotoxic organophosphorus agents and several beta-cyclodesxtrin derivatives were obtained.
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New opportunities with the Duff reaction.
Nicolas Masurier,Emmanuel Moreau,Claire Lartigue,Vincent Gaumet,Jean-Michel Chezal,Annie Heitz,Jean-Claude Teulade,Olivier Chavignon +7 more
TL;DR: The formation of an aminomethyl intermediate in the Duff reaction mechanism is unequivocally demonstrated and provides a useful route to aldehydes for compounds bearing sensitive amide functions.
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Imidazopyridine-fused [1,3]-diazepinones: synthesis and antiproliferative activity.
Audrey Gallud,Ophélie Vaillant,Ludovic T. Maillard,Dominique P. Arama,Joëlle Dubois,Marie Maynadier,Vincent Lisowski,Marcel Garcia,Jean Martinez,Nicolas Masurier +9 more
TL;DR: This compound led to deep cell morphological changes and revealed to be an inhibitor of the Hepatocyte progenitor kinase-like kinase (HGK), which is known to be implicated in the migration, adhesion and invasion of various tumor cells.