N
Nicole Harr
Researcher at Columbia University
Publications - 2
Citations - 53
Nicole Harr is an academic researcher from Columbia University. The author has contributed to research in topics: Gene & Chemistry. The author has co-authored 1 publications.
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A programmable encapsulation system improves delivery of therapeutic bacteria in mice
Tetsuhiro Harimoto,Jaeseung Hahn,Yu-Yu Chen,Jong Seong Im,Joanna Zhang,Nicholas Hou,Fang-fang Li,Courtney Coker,Kelsey E. Gray,Nicole Harr,Sreyan Chowdhury,Kelly Pu,Clare A. Nimura,Nicholas Arpaia,Kam W. Leong,Tal Danino +15 more
TL;DR: In this article , a genetically encoded microbial encapsulation system with tunable and dynamic expression of surface capsular polysaccharides was developed to enhance systemic delivery of living bacteria therapies for treating a broad array of cancers.
Posted ContentDOI
A programmable probiotic encapsulation system enhances therapeutic delivery in vivo
Tetsuhiro Harimoto,Jaeseung Hahn,Yu-Yu Chen,Jongwon Im,Joanna Zhang,Nicholas Hou,Fangda Li,Courtney Coker,Kelsey Gray,Nicole Harr,Sreyan Chowdhury,Kelly Pu,Clare Nimura,Nicholas Arpaia,Kam W. Leong,Kam W. Leong,Tal Danino +16 more
TL;DR: In this paper, a genetically encoded microbial encapsulation system with tunable and dynamic expression of surface capsular polysaccharides was developed to enhance therapeutic delivery, which enabled tunable immunogenicity and survivability of the probiotic Escherichia coli.