N
Nicolette Farman
Researcher at French Institute of Health and Medical Research
Publications - 149
Citations - 8554
Nicolette Farman is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Aldosterone & Mineralocorticoid receptor. The author has an hindex of 50, co-authored 148 publications receiving 7992 citations. Previous affiliations of Nicolette Farman include Pierre-and-Marie-Curie University & University of Paris.
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Journal ArticleDOI
Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis.
Alejandra Daruich,Alexandre Matet,Ali Dirani,Elodie Bousquet,Min Zhao,Nicolette Farman,Frederic Jaisser,Francine Behar-Cohen +7 more
TL;DR: The aim of this review is to recapitulate the clinical understanding of CSCR, with an emphasis on the most recent findings on epidemiology, risk factors, clinical and imaging diagnosis, and treatments options, and the novel mineralocorticoid pathway hypothesis.
Journal ArticleDOI
Cloning and expression of a novel pH-sensitive two pore domain K^+ channel from human kidney
Roberto V. Reyes,Fabrice Duprat,Florian Lesage,Michel Fink,Miguel Salinas,Nicolette Farman,Michel Lazdunski +6 more
TL;DR: In human and mouse, TASK-2 is mainly expressed in the kidney, where in situ hybridization shows that it is localized in cortical distal tubules and collecting ducts, suggesting that TASk-2 could play an important role in renal K+ transport.
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Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy
Min Zhao,Isabelle Célérier,Elodie Bousquet,Jean-Claude Jeanny,Laurent Jonet,Michèle Savoldelli,Olivier Offret,Antoine Curan,Nicolette Farman,Frederic Jaisser,Francine Behar-Cohen +10 more
TL;DR: The results identify MR signaling as a pathway controlling choroidal vascular bed relaxation and provide a pathogenic link with human CSCR, which suggests that blockade of MR could be used therapeutically to reverse choroid vasculopathy.
Journal ArticleDOI
Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor
Marc Lombès,M. E. Oblin,J M Gasc,Etienne-Emile Baulieu,Nicolette Farman,Jean-Pierre Bonvalet +5 more
TL;DR: The results clearly demonstrate the presence of MRs in the cardiovascular system and supports the possibility of direct aldosterone actions in the heart and blood vessels.
Journal ArticleDOI
Prerequisite for cardiac aldosterone action. Mineralocorticoid receptor and 11 beta-hydroxysteroid dehydrogenase in the human heart.
Marc Lombès,Nadia Alfaidy,Emmanuel Eugène,Alessandro Lessana,Nicolette Farman,Jean-Pierre Bonvalet +5 more
TL;DR: It is demonstrated that MR is coexpressed with 11-HSD in human heart, which thus possesses the cellular machinery required for direct aldosterone action.