N
Nidhi Patel
Publications - 1
Citations - 38
Nidhi Patel is an academic researcher. The author has contributed to research in topics: Nucleic acid & DNA. The author has an hindex of 1, co-authored 1 publications receiving 1 citations.
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Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics
Eric Nalefski,Nidhi Patel,Philip J.Y. Leung,Zeba Islam,Remy M. Kooistra,Ishira Parikh,Estelle Marion,Gavin J. Knott,Gavin J. Knott,Jennifer A. Doudna,Anne-Laure M. Le Ny,Damian Madan +11 more
TL;DR: In this article, the authors examined the kinetics of single-turnover target and multi-turnoff trans-nuclease activities of both enzymes and showed that these enzymes are kinetically adapted to play distinct roles in bacterial adaptive immunity and show how kinetic analysis can be applied to CRISPR-based diagnostics.