N
Nigel A. Cunliffe
Researcher at University of Liverpool
Publications - 195
Citations - 8593
Nigel A. Cunliffe is an academic researcher from University of Liverpool. The author has contributed to research in topics: Rotavirus & Rotavirus vaccine. The author has an hindex of 45, co-authored 188 publications receiving 7822 citations. Previous affiliations of Nigel A. Cunliffe include Public Health England & Malawi-Liverpool-Wellcome Trust Clinical Research Programme.
Papers
More filters
Journal ArticleDOI
Effect of human rotavirus vaccine on severe diarrhea in African infants.
Shabir A. Madhi,Nigel A. Cunliffe,Duncan Steele,Desiree Witte,Mari Kirsten,Cheryl Louw,Bagrey Ngwira,John C. Victor,Paul Gillard,Brigitte Cheuvart,Htay Htay Han,Kathleen M. Neuzil +11 more
TL;DR: Human rotvirus vaccine significantly reduced the incidence of severe rotavirus gastroenteritis among African infants during the first year of life.
Journal ArticleDOI
Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs.
Jon R. Gentsch,Ashley R. Laird,Brittany Bielfelt,Dixie D. Griffin,Krisztián Bányai,M. Ramachandran,Vivek Jain,Nigel A. Cunliffe,Osamu Nakagomi,Carl D. Kirkwood,Thea Kølsen Fischer,Umesh D. Parashar,Joseph S. Bresee,Baoming Jiang,Roger I. Glass +14 more
TL;DR: Strain surveillance helps to determine whether the most prevalent local strains are likely to be covered by the serotype antigens found in current vaccines, and identified globally (G9) or regionally (G5, G8, and P2A[6]) common serotypes not cover by the reassortant vaccines that have undergone efficacy trials.
Reference EntryDOI
Vaccines for preventing rotavirus diarrhoea: vaccines in use
Karla Soares-Weiser,Harriet MacLehose,Hanna Bergman,Irit Ben-Aharon,Sukrti Nagpal,Elad Goldberg,Femi Pitan,Nigel A. Cunliffe +7 more
TL;DR: Evaluating rotavirus vaccines approved for use (RV1, RV5, and LLR) for preventingRotavirus diarrhoea in children with high-mortality rates found that RV1 probably prevents 40% of severe all-cause diarrhoeA episodes, and RV5probably prevents 40%, based on one large multicentre trial in Latin America and Finland.
Journal Article
Epidemiology of rotavirus diarrhoea in Africa: a review to assess the need for rotavirus immunization.
TL;DR: C cumulative experience from 15 African countries suggests that rotavirus is the most important cause of severe diarrhoea in African children and that most strains in circulation today belong to common G types that are included in reassortant vaccines.
Journal ArticleDOI
Molecular epidemiology of noroviruses associated with acute sporadic gastroenteritis in children: Global distribution of genogroups, genotypes and GII.4 variants
T. N. Hoa Tran,Eamonn Trainor,Toyoko Nakagomi,Toyoko Nakagomi,Nigel A. Cunliffe,Osamu Nakagomi,Osamu Nakagomi +6 more
TL;DR: A systematic review of studies performed after 2000 to clarify the genotypic distribution of noroviruses in children (≤18 years of age) with sporadic acute gastroenteritis found that Genogroup GII norovirus was the most prevalent, accounting for 96% of all sporadic infections.