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Niklaus Schaefer
Researcher at University of Lausanne
Publications - 102
Citations - 2695
Niklaus Schaefer is an academic researcher from University of Lausanne. The author has contributed to research in topics: Medicine & PET-CT. The author has an hindex of 25, co-authored 85 publications receiving 2058 citations. Previous affiliations of Niklaus Schaefer include Johns Hopkins University School of Medicine & University of Zurich.
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Journal ArticleDOI
Non-Hodgkin lymphoma and Hodgkin disease: coregistered FDG PET and CT at staging and restaging--do we need contrast-enhanced CT?
Niklaus Schaefer,Thomas F. Hany,Christian Taverna,Burkhardt Seifert,Katrin D. M. Stumpe,Gustav K. von Schulthess,Gerhard W. Goerres +6 more
TL;DR: PET/CT performed with nonenhanced CT is more sensitive and specific than is contrast-enhancedCT for evaluation of lymph node and organ involvement, especially regarding exclusion of disease, in patients with Hodgkin disease and high-grade non-Hodgkin lymphoma.
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Bone involvement in patients with lymphoma: the role of FDG-PET/CT.
TL;DR: In patients with FDG-avid bone lesions,FDG-PET is superior to CT alone or in combination with unilateral BMB in detecting bone marrow involvement, leading to upstaging in a relevant proportion of patients.
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New derivatives of vitamin B12 show preferential targeting of tumors.
Robert Waibel,Hansjörg Treichler,Niklaus Schaefer,Dave R. van Staveren,Stefan Mundwiler,Susanne Kunze,Martin Küenzi,Roger Alberto,Jakob Nuesch,Alexander Knuth,Holger Moch,Roger Schibli,Pius A. Schubiger +12 more
TL;DR: The objective of this work is to exploit the supply route of vitamin B12 to deliver new derivatives of this vital vitamin to hyperproliferative cells and identified transcobalamin I on tumors as a possible new receptor for this preferential accumulation of vitamin-mediated targeting.
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Automatic lesion detection and segmentation of 18F-FET PET in gliomas: A full 3D U-Net convolutional neural network study.
TL;DR: With relatively high performance, it was proposed the first full 3D automated procedure for segmentation of 18F-FET PET brain images of patients with different gliomas using a U-Net CNN architecture.
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Clinical impact of 18F-choline PET/CT in patients with recurrent prostate cancer
Jan Soyka,Marco A. Muster,Daniel T. Schmid,Burkhardt Seifert,Ulrike Schick,Raymond Miralbell,Sandra Jorcano,Kathrin Zaugg,Hans-Helge Seifert,Patrick Veit-Haibach,Klaus Strobel,Niklaus Schaefer,Daniela B. Husarik,Thomas F. Hany +13 more
TL;DR: In this paper, the clinical value of 18F-fluorocholine PET/CT (CH-PET/CT) in treatment decisions in patients with recurrent prostate cancer (rPCA) was investigated.