N
Nikos Chronis
Researcher at University of Michigan
Publications - 46
Citations - 3299
Nikos Chronis is an academic researcher from University of Michigan. The author has contributed to research in topics: Numerical aperture & Microlens. The author has an hindex of 18, co-authored 45 publications receiving 3033 citations. Previous affiliations of Nikos Chronis include Howard Hughes Medical Institute & University of California, Berkeley.
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Journal ArticleDOI
Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans
Sreekanth H. Chalasani,Nikos Chronis,Makoto Tsunozaki,Jesse M. Gray,Daniel Ramot,Miriam B. Goodman,Cornelia I. Bargmann +6 more
TL;DR: Information processing by Caenorhabditis elegans olfactory neurons and interneurons resembles information flow from vertebrate photoreceptors to ‘OFF” bipolar and ‘ON’ bipolar neurons, indicating a conserved or convergent strategy for sensory information processing.
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Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans
TL;DR: Two microfluidic chips, the 'behavior' chip and the 'olfactory' chip, are developed for imaging of neuronal and behavioral responses in C. elegans and revealed previously unknown properties of AVA and ASH neurons.
Journal ArticleDOI
Electrothermally activated SU-8 microgripper for single cell manipulation in solution
Nikos Chronis,Luke P. Lee +1 more
TL;DR: In this paper, the SU-8-based micro gripper that can operate in physiological ionic solutions is presented, which consists of two "hot-and-cold" arm actuators that are fabricated in a two-mask surface micromachining process.
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Neurons Detect Increases and Decreases in Oxygen Levels Using Distinct Guanylate Cyclases
Manuel Zimmer,Jesse M. Gray,Navin Pokala,Andy J. Chang,David S. Karow,Michael A. Marletta,Martin L. Hudson,David B. Morton,Nikos Chronis,Cornelia I. Bargmann +9 more
TL;DR: In C. elegans, a homeostatic preference for intermediate oxygen (O2) levels requires cGMP signaling through soluble guanylate cyclases (sGCs), proteins that bind gases through an associated heme group as discussed by the authors.
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Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies
Samuel X. Guo,Frederic Bourgeois,Trushal Vijaykumar Chokshi,Nicholas J. Durr,Massimo A. Hilliard,Nikos Chronis,Adela Ben-Yakar +6 more
TL;DR: Using the 'nanoaxotomy' chip, it is discovered that axonal regeneration occurs much faster than previously described, and notably, the distal fragment of the severed axon regrows in the absence of anesthetics.