N
Nilgün Gedik
Researcher at University of Duisburg-Essen
Publications - 9
Citations - 702
Nilgün Gedik is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Ischemic preconditioning & Cardioprotection. The author has an hindex of 6, co-authored 9 publications receiving 597 citations.
Papers
More filters
Journal ArticleDOI
Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trial
Matthias Thielmann,Eva Kottenberg,Petra Kleinbongard,Daniel Wendt,Nilgün Gedik,Susanne Pasa,Vivien Price,Konstantinos Tsagakis,Markus Neuhäuser,Jürgen Peters,Heinz Jakob,Gerd Heusch +11 more
TL;DR: Remote ischaemic preconditioning provided perioperative myocardial protection and improved the prognosis of patients undergoing elective CABG surgery.
Journal ArticleDOI
Intraaortic Protection From Embolization in Patients Undergoing Transaortic Transcatheter Aortic Valve Implantation.
Daniel Wendt,Petra Kleinbongard,Stephan Knipp,Fadi Al-Rashid,Nilgün Gedik,Karim El Chilali,Sebastian Schweter,Marc Schlamann,Philipp Kahlert,Markus Neuhäuser,Michael Forsting,Raimund Erbel,Gerd Heusch,Heinz Jakob,Matthias Thielmann +14 more
TL;DR: The EMBOL-X protection device (Edwards Lifesciences, Irvine, CA) is positioned within the ascending aorta to capture such debris as discussed by the authors, which results in the dislodgement of debris with risk of cerebral lesions or stroke.
Journal ArticleDOI
Pleiotropic, heart rate-independent cardioprotection by ivabradine.
TL;DR: In pigs, ivabradine reduces infarct size even when given only at reperfusion and in the absence of heart rate reduction and the mechanism of this non‐heart rate‐related cardioprotection is unknown.
Journal ArticleDOI
No Evidence for Activated Autophagy in Left Ventricular Myocardium at Early Reperfusion with Protection by Remote Ischemic Preconditioning in Patients Undergoing Coronary Artery Bypass Grafting
Nilgün Gedik,Matthias Thielmann,Eva Kottenberg,Jürgen Peters,Heinz Jakob,Gerd Heusch,Petra Kleinbongard +6 more
TL;DR: Protection through RIPC in patients undergoing CABG surgery does not appear to be associated with enhanced autophagy in LV myocardium at early reperfusion.
Journal ArticleDOI
Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularization
Nilgün Gedik,Eva Kottenberg,Matthias Thielmann,Ulrich H. Frey,Heinz Jakob,Jürgen Peters,Gerd Heusch,Petra Kleinbongard +7 more
TL;DR: Arterial plasma concentrations of 25 different cytokines, growth hormones, and other factors which have previously been associated with cardioprotection are determined, before/after ischemic cardioplegic arrest in CABG patients and only interleukin-1α possibly fulfills the criteria which would be expected from a substance to be released in response to RIPC.