Nina Kim

TL;DR: Novel specialized proresolving mediators—eicosanoids with critical roles in resolution—may act through PPARγ modulation to promote resolution, providing another exciting area of therapeutic potential for this receptor.

TL;DR: This study investigated the ability of the SPM 17-HDHA to enhance the adaptive immune response using an OVA immunization model and a preclinical influenza vaccination mouse model, and reported the first report on the biological effects of ω-3-derived SPMs on the humoral immune response.

TL;DR: It is hypothesized that platelet transcription factors are not vestigial remnants from megakaryocytes, but have important, if only partly understood functions, and at the very least, platelets are an ideal model cell to dissect out the non-genomic roles of transcription factors in nucleated cells.

TL;DR: It is demonstrated that certain SPMs inhibit the differentiation of IgE‐producing B cells, without being broadly immune suppressive, representing a novel class of potential therapeutics for IgE-driven diseases such as asthma and allergy.

TL;DR: LXB4 boosts memory B cell activation through COX2 and suggests that LXB4 can serve as a new vaccine adjuvant, which is a first for the first time, to the authors' knowledge, revealed.