N
Nobuyuki Takahashi
Researcher at Kyoto University
Publications - 260
Citations - 8813
Nobuyuki Takahashi is an academic researcher from Kyoto University. The author has contributed to research in topics: Peroxisome proliferator-activated receptor & Adipose tissue. The author has an hindex of 47, co-authored 223 publications receiving 7831 citations. Previous affiliations of Nobuyuki Takahashi include Kanagawa University & Graduate University for Advanced Studies.
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Ezrin/Radixin/Moesin (ERM) Proteins Bind to a Positively Charged Amino Acid Cluster in the Juxta-Membrane Cytoplasmic Domain of CD44, CD43, and ICAM-2
Shigenobu Yonemura,Motohiro Hirao,Yoshinori Doi,Nobuyuki Takahashi,Takahisa Kondo,Sachiko Tsukita,Shoichiro Tsukita +6 more
TL;DR: It is concluded that ERM proteins bind to integral membrane proteins bearing a positively charged amino acid cluster in their juxta-membrane cytoplasmic domain.
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PPARγ coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
Yasutomi Kamei,Hiroshi Ohizumi,Yasushi Fujitani,Tomoyuki Nemoto,Toshiya Tanaka,Nobuyuki Takahashi,Teruo Kawada,Masamitsu Miyoshi,Osamu Ezaki,Akira Kakizuka +9 more
TL;DR: It is demonstrated that PGC-1β/ERRL1 can function as a protein ligand of ERR, and that its level contributes to the control of energy balance in vivo, and provide a strategy for developing novel antiobesity drugs.
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Oxytocin receptor-deficient mice developed late-onset obesity.
Yuki Takayanagi,Yoshiyuki Kasahara,Tatsushi Onaka,Nobuyuki Takahashi,Teruo Kawada,Katsuhiko Nishimori +5 more
TL;DR: It is demonstrated that oxytocin receptor plays essential roles in the regulation of energy homeostasis with late-onset obesity with increases in abdominal fat pads and fasting plasma triglycerides in Oxtr−/− mice.
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Dual action of isoprenols from herbal medicines on both PPARγ and PPARα in 3T3-L1 adipocytes and HepG2 hepatocytes
Nobuyuki Takahashi,Teruo Kawada,Tsuyoshi Goto,Takayuki Yamamoto,Aki Taimatsu,Naoko Matsui,Kazuhiro Kimura,Masayuki Saito,Masashi Hosokawa,Kazuo Miyashita,Tohru Fushiki +10 more
TL;DR: The results suggest that herbal medicines containing isoprenols with dual action on both PPARγ and PPARα can be of interest for the amelioration of lipid metabolic disorders associated with diabetes.
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Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death.
TL;DR: Blocking the VSOR Cl− channel prevented cell death in not only epithelial and cardiac cells, but also other cell types, by inhibiting the induction of AVD and subsequent apoptotic events.