Y
Yuki Takayanagi
Researcher at Jichi Medical University
Publications - 45
Citations - 2825
Yuki Takayanagi is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Oxytocin receptor & Oxytocin. The author has an hindex of 20, co-authored 40 publications receiving 2413 citations. Previous affiliations of Yuki Takayanagi include University of Edinburgh & Laboratory of Molecular Biology.
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Journal ArticleDOI
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
Yuki Takayanagi,Masahide Yoshida,Isadora F. Bielsky,Heather E. Ross,Masaki Kawamata,Tatsushi Onaka,Teruyuki Yanagisawa,Tadashi Kimura,Martin M. Matzuk,Larry J. Young,Katsuhiko Nishimori +10 more
TL;DR: It is demonstrated that OXTR plays a critical role in regulating several aspects of social behavior and may have important implications for developmental psychiatric disorders characterized by deficits in social behavior.
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Evidence That Oxytocin Exerts Anxiolytic Effects via Oxytocin Receptor Expressed in Serotonergic Neurons in Mice
Masahide Yoshida,Yuki Takayanagi,Kiyoshi Inoue,Tadashi Kimura,Larry J. Young,Tatsushi Onaka,Katsuhiko Nishimori +6 more
TL;DR: This is the first demonstration that oxytocin may regulate serotonin release and exert anxiolytic effects via direct activation of Oxytocin receptor expressed in serotonergic neurons of the raphe nuclei.
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Oxytocin receptor-deficient mice developed late-onset obesity.
Yuki Takayanagi,Yoshiyuki Kasahara,Tatsushi Onaka,Nobuyuki Takahashi,Teruo Kawada,Katsuhiko Nishimori +5 more
TL;DR: It is demonstrated that oxytocin receptor plays essential roles in the regulation of energy homeostasis with late-onset obesity with increases in abdominal fat pads and fasting plasma triglycerides in Oxtr−/− mice.
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An intrinsic vasopressin system in the olfactory bulb is involved in social recognition.
Vicky A. Tobin,Hirofumi Hashimoto,Douglas W. Wacker,Yuki Takayanagi,Kristina Langnaese,Celine Caquineau,Julia Noack,Rainer Landgraf,Tatsushi Onaka,Gareth Leng,Simone Meddle,Mario Engelmann,Mike Ludwig +12 more
TL;DR: It is reported that the rat olfactory bulb contains a large population of interneurons which express vasopressin, that blocking the actions of vasoppressin in the ofactory bulb impairs the social recognition abilities of rats and that vasopgressin agonists and antagonists can modulate the processing of information by olactory bulb neurons.
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Roles of Oxytocin Neurones in the Control of Stress, Energy Metabolism, and Social Behaviour
TL;DR: The oxytocin–oxytocin receptor system is a therapeutic target for the promotion of human health and shows anxiolytic, anorexic and pro‐social actions.