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Noelle Lucke-Wold
Researcher at West Virginia University
Publications - 17
Citations - 558
Noelle Lucke-Wold is an academic researcher from West Virginia University. The author has contributed to research in topics: Stroke & Lymphocyte. The author has an hindex of 12, co-authored 15 publications receiving 433 citations.
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Journal ArticleDOI
A population-based incidence of acute large vessel occlusions and thrombectomy eligible patients indicates significant potential for growth of endovascular stroke therapy in the USA.
Ansaar T Rai,Aaron E Seldon,SoHyun Boo,Paul S Link,Jennifer Domico,Abdul R Tarabishy,Noelle Lucke-Wold,Jeffrey S Carpenter +7 more
TL;DR: A current estimated annual thrombectomy rate of three procedures per 100 000 people indicates significant potential increase in the volume of endovascular procedures and the need to develop systems of care.
Journal ArticleDOI
A population-based incidence of M2 strokes indicates potential expansion of large vessel occlusions amenable to endovascular therapy
Ansaar T Rai,Jennifer Domico,Chelsea Buseman,Abdul R Tarabishy,Daniel Fulks,Noelle Lucke-Wold,SoHyun Boo,Jeffrey S Carpenter +7 more
TL;DR: Patients with M2 occlusions and higher baseline deficits (NIHSS score ≥9) may benefit from endovascular therapy, thus potentially expanding the category of acute ischemic strokes amenable to intervention.
Journal ArticleDOI
Circulating extracellular DNA levels are acutely elevated in ischaemic stroke and associated with innate immune system activation.
Grant C. O’Connell,Ashley B Petrone,Connie S. Tennant,Noelle Lucke-Wold,Yasser Kabbani,Abdul R Tarabishy,Paul D. Chantler,Taura L. Barr +7 more
TL;DR: Assessment of peripheral blood cfDNA levels may be useful for the identification of ischaemic stroke in the acute care setting, and associative evidence that cfDNA is a potential activator of the peripheral innate immune system in response to cerebral ischaemia is provided.
Journal ArticleDOI
Machine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischaemic stroke
Grant C. O’Connell,Ashley B Petrone,Madison B. Treadway,Connie S. Tennant,Noelle Lucke-Wold,Paul D. Chantler,Taura L. Barr +6 more
TL;DR: The transcriptional pattern identified in this study shows strong diagnostic potential, and warrants further evaluation to determine its true clinical efficacy.
Journal ArticleDOI
Neuroprotection for Ischemic Stroke: Moving Past Shortcomings and Identifying Promising Directions
Ryan C. Turner,Brandon Lucke-Wold,Noelle Lucke-Wold,Alisa S. Elliott,Aric F. Logsdon,Charles L. Rosen,Jason D. Huber +6 more
TL;DR: The role of inflammation in stroke and in particular, the role of inflammatory cell recruitment and macrophage phenotype in the inflammatory process is reviewed and an increasing role of neuro-immune crosstalk is indicated, which has led to increased interest in identification of peripheral biomarkers indicative of neural injury.