C
Charles L. Rosen
Researcher at West Virginia University
Publications - 92
Citations - 3050
Charles L. Rosen is an academic researcher from West Virginia University. The author has contributed to research in topics: Stroke & Traumatic brain injury. The author has an hindex of 32, co-authored 92 publications receiving 2479 citations.
Papers
More filters
Journal ArticleDOI
Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review
Brandon Lucke-Wold,Aric F. Logsdon,Branavan Manoranjan,Ryan C. Turner,Evan McConnell,George Edward Vates,Jason D. Huber,Charles L. Rosen,J. Simard +8 more
TL;DR: An overview of how neuroinflammation relates to secondary outcomes such as vasospasm after aneurysmal rupture is provided and to critically discuss pharmaceutical agents that warrant further investigation for the treatment of subarachnoid hemorrhage.
Journal ArticleDOI
Early disruptions of the blood-brain barrier may contribute to exacerbated neuronal damage and prolonged functional recovery following stroke in aged rats
TL;DR: Results indicate that aged rats suffer larger infarctions, reduced functional recovery and increased BBB disruption preceding observable neuronal injury.
OtherDOI
Role of Microvascular Disruption in Brain Damage from Traumatic Brain Injury
Aric F. Logsdon,Brandon Lucke-Wold,Ryan C. Turner,Jason D. Huber,Charles L. Rosen,James W. Simpkins +5 more
TL;DR: With appropriate intervention following TBI, the vascular network can be maintained and the cellular repair process possibly improved to aid in the recovery of cellular homeostasis, as well as preventing the development of neuropsychiatric symptoms.
Journal ArticleDOI
Traumatic brain injury and epilepsy: Underlying mechanisms leading to seizure
Brandon Lucke-Wold,Linda Nguyen,Ryan C. Turner,Aric F. Logsdon,Yi-Wen Chen,Kelly E. Smith,Jason D. Huber,Rae R. Matsumoto,Rae R. Matsumoto,Charles L. Rosen,Eric S. Tucker,Erich Richter +11 more
TL;DR: By increasing understanding about post-traumatic epilepsy and injury expansion over time, it will be possible to design better treatments with specific molecular targets to prevent late-onset seizure occurrence following traumatic brain injury.
Journal ArticleDOI
Linking Traumatic Brain Injury to Chronic Traumatic Encephalopathy: Identification of Potential Mechanisms Leading to Neurofibrillary Tangle Development
Brandon Lucke-Wold,Ryan C. Turner,Aric F. Logsdon,Julian E. Bailes,Jason D. Huber,Charles L. Rosen +5 more
TL;DR: Understanding the mechanistic link between acute brain injury and chronic neurodegeneration will facilitate the development of appropriate diagnostic and therapeutic options for CTE and other related disorders.