B
Brandon Lucke-Wold
Researcher at West Virginia University
Publications - 189
Citations - 2530
Brandon Lucke-Wold is an academic researcher from West Virginia University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 23, co-authored 94 publications receiving 1760 citations. Previous affiliations of Brandon Lucke-Wold include University of Chicago.
Papers
More filters
Journal ArticleDOI
Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review
Brandon Lucke-Wold,Aric F. Logsdon,Branavan Manoranjan,Ryan C. Turner,Evan McConnell,George Edward Vates,Jason D. Huber,Charles L. Rosen,J. Simard +8 more
TL;DR: An overview of how neuroinflammation relates to secondary outcomes such as vasospasm after aneurysmal rupture is provided and to critically discuss pharmaceutical agents that warrant further investigation for the treatment of subarachnoid hemorrhage.
Journal ArticleDOI
Role of sigma-1 receptors in neurodegenerative diseases.
Linda Nguyen,Brandon Lucke-Wold,Shona A. Mookerjee,John Z. Cavendish,Matthew J. Robson,Anna L. Scandinaro,Rae R. Matsumoto +6 more
TL;DR: An overview of the biological mechanisms frequently associated with neurodegeneration is provided, and how sigma-1 receptors may alter these mechanisms to preserve or restore neuronal function is discussed.
OtherDOI
Role of Microvascular Disruption in Brain Damage from Traumatic Brain Injury
Aric F. Logsdon,Brandon Lucke-Wold,Ryan C. Turner,Jason D. Huber,Charles L. Rosen,James W. Simpkins +5 more
TL;DR: With appropriate intervention following TBI, the vascular network can be maintained and the cellular repair process possibly improved to aid in the recovery of cellular homeostasis, as well as preventing the development of neuropsychiatric symptoms.
Journal ArticleDOI
Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae
Onder Albayram,Asami Kondo,Rebekah Mannix,Colin Smith,Cheng-Yu Tsai,Chenyu Li,Megan K. Herbert,Jianhua Qiu,Michael C. Monuteaux,Jane A. Driver,Jane A. Driver,Sandra C. Yan,William B. Gormley,Ava M. Puccio,David O. Okonkwo,Brandon Lucke-Wold,Julian E. Bailes,William P. Meehan,Mark L. Zeidel,Kun Ping Lu,Xiao Zhen Zhou +20 more
TL;DR: It is found that in human samples obtained post TBI due to a variety of causes, cis P-tau is induced in cortical axons and cerebrospinal fluid and positively correlates with axonal injury and clinical outcome.
Journal ArticleDOI
Traumatic brain injury and epilepsy: Underlying mechanisms leading to seizure
Brandon Lucke-Wold,Linda Nguyen,Ryan C. Turner,Aric F. Logsdon,Yi-Wen Chen,Kelly E. Smith,Jason D. Huber,Rae R. Matsumoto,Rae R. Matsumoto,Charles L. Rosen,Eric S. Tucker,Erich Richter +11 more
TL;DR: By increasing understanding about post-traumatic epilepsy and injury expansion over time, it will be possible to design better treatments with specific molecular targets to prevent late-onset seizure occurrence following traumatic brain injury.