N
Norihiro Sato
Researcher at University of Occupational and Environmental Health Japan
Publications - 168
Citations - 11277
Norihiro Sato is an academic researcher from University of Occupational and Environmental Health Japan. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 58, co-authored 156 publications receiving 10576 citations. Previous affiliations of Norihiro Sato include Kyushu University & Johns Hopkins University.
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Journal ArticleDOI
Biomarker Discovery from Pancreatic Cancer Secretome Using a Differential Proteomic Approach
Mads Grønborg,Mads Grønborg,Troels Zaccharias Glahn Kristiansen,Troels Zaccharias Glahn Kristiansen,Akiko Iwahori,Rubens Chang,Raghunath Reddy,Norihiro Sato,Henrik Molina,Henrik Molina,Ole N. Jensen,Ralph H. Hruban,Michael C. Goggins,Anirban Maitra,Akilesh Pandey +14 more
TL;DR: Stable isotope labeling with amino acids in cell culture (SILAC) method is demonstrated to compare the secreted proteins (secretome) from pancreatic cancer-derived cells with that from non-neoplastic pancreatic ductal cells, confirming the validity of this approach.
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Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays.
Christine A. Iacobuzio-Donahue,Anirban Maitra,Mari Olsen,Anson W. Lowe,N. Tjarda van Heek,Christophe Rosty,Kimberly Walter,Norihiro Sato,Antony R. Parker,Raheela Ashfaq,Elizabeth M. Jaffee,Byungwoo Ryu,Jessa Jones,James R. Eshleman,Charles J. Yeo,John L. Cameron,Scott E. Kern,Ralph H. Hruban,Patrick O. Brown,Michael Goggins +19 more
TL;DR: The genes and expressed sequence tags presented in this study provide clues to the pathobiology of pancreatic cancer and implicate a large number of potentially new molecular markers for the detection and treatment of Pancreatic cancer.
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Peritumoral Fibroblast SPARC Expression and Patient Outcome With Resectable Pancreatic Adenocarcinoma
Jeffrey R. Infante,Hiroyuki Matsubayashi,Norihiro Sato,James Tonascia,Alison P. Klein,Taylor A. Riall,Charles J. Yeo,Christine A. Iacobuzio-Donahue,Michael Goggins +8 more
TL;DR: The expression of SPARC by peritumoral fibroblasts portends a poorer prognosis for patients with pancreatic cancer.
Journal Article
Discovery of Novel Targets for Aberrant Methylation in Pancreatic Carcinoma Using High-Throughput Microarrays
Norihiro Sato,Noriyoshi Fukushima,Anirban Maitra,Hiroyuki Matsubayashi,Charles J. Yeo,John L. Cameron,Ralph H. Hruban,Michael Goggins +7 more
TL;DR: A substantial number of genes are induced by 5Aza-dC treatment of pancreatic cancer cells, and many of them may represent novel targets for aberrant methylation in pancreatic carcinoma.
Journal ArticleDOI
Radiation to Stromal Fibroblasts Increases Invasiveness of Pancreatic Cancer Cells through Tumor-Stromal Interactions
Kenoki Ohuchida,Kazuhiro Mizumoto,Mitsuhiko Murakami,Li Wu Qian,Norihiro Sato,Eishi Nagai,Kunio Matsumoto,Toshikazu Nakamura,Masao Tanaka +8 more
TL;DR: The data suggest that invasive potential of certain pancreatic cancer cells is enhanced by soluble mediator(s) released from irradiated fibroblasts possibly through up-regulation of c-Met expression/phosphorylation and mitogen-activated protein kinase activity in pancreaticcancer cells.