THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

The Design and Analysis of Experiments

SUMMARY
We describe best-fitting angular velocities and MORVEL, a new closure-enforced set of angular velocities for the geologically current motions of 25 tectonic plates that collectively occupy 97 per cent of Earth's surface. Seafloor spreading rates and fault azimuths are used to determine the motions of 19 plates bordered by mid-ocean ridges, including all the major plates. Six smaller plates with little or no connection to the mid-ocean ridges are linked to MORVEL with GPS station velocities and azimuthal data. By design, almost no kinematic information is exchanged between the geologically determined and geodetically constrained subsets of the global circuit—MORVEL thus averages motion over geological intervals for all the major plates. Plate geometry changes relative to NUVEL-1A include the incorporation of Nubia, Lwandle and Somalia plates for the former Africa plate, Capricorn, Australia and Macquarie plates for the former Australia plate, and Sur and South America plates for the former South America plate. MORVEL also includes Amur, Philippine Sea, Sundaland and Yangtze plates, making it more useful than NUVEL-1A for studies of deformation in Asia and the western Pacific. Seafloor spreading rates are estimated over the past 0.78 Myr for intermediate and fast spreading centres and since 3.16 Ma for slow and ultraslow spreading centres. Rates are adjusted downward by 0.6–2.6 mm yr−1 to compensate for the several kilometre width of magnetic reversal zones. Nearly all the NUVEL-1A angular velocities differ significantly from the MORVEL angular velocities. The many new data, revised plate geometries, and correction for outward displacement thus significantly modify our knowledge of geologically current plate motions. MORVEL indicates significantly slower 0.78-Myr-average motion across the Nazca–Antarctic and Nazca–Pacific boundaries than does NUVEL-1A, consistent with a progressive slowdown in the eastward component of Nazca plate motion since 3.16 Ma. It also indicates that motions across the Caribbean–North America and Caribbean–South America plate boundaries are twice as fast as given by NUVEL-1A. Summed, least-squares differences between angular velocities estimated from GPS and those for MORVEL, NUVEL-1 and NUVEL-1A are, respectively, 260 per cent larger for NUVEL-1 and 50 per cent larger for NUVEL-1A than for MORVEL, suggesting that MORVEL more accurately describes historically current plate motions. Significant differences between geological and GPS estimates of Nazca plate motion and Arabia–Eurasia and India–Eurasia motion are reduced but not eliminated when using MORVEL instead of NUVEL-1A, possibly indicating that changes have occurred in those plate motions since 3.16 Ma. The MORVEL and GPS estimates of Pacific–North America plate motion in western North America differ by only 2.6 ± 1.7 mm yr−1, ≈25 per cent smaller than for NUVEL-1A. The remaining difference for this plate pair, assuming there are no unrecognized systematic errors and no measurable change in Pacific–North America motion over the past 1–3 Myr, indicates deformation of one or more plates in the global circuit. Tests for closure of six three-plate circuits indicate that two, Pacific–Cocos–Nazca and Sur–Nubia–Antarctic, fail closure, with respective linear velocities of non-closure of 14 ± 5 and 3 ± 1 mm yr−1 (95 per cent confidence limits) at their triple junctions. We conclude that the rigid plate approximation continues to be tremendously useful, but—absent any unrecognized systematic errors—the plates deform measurably, possibly by thermal contraction and wide plate boundaries with deformation rates near or beneath the level of noise in plate kinematic data.

Geologically current plate motions

Roger Sheldon (1942) received a PhD in organic chemistry from the University of Leicester (UK) in 1967. This was followed by post-doctoral studies with Prof. Jay Kochi in the U.S. From 1969 to 1980 he was with Shell Research in Amsterdam and from 1980 to 1990 he was R&D Director of DSM Andeno. In 1991 he moved to his present position as Professor of organic chemistry and catalysis at the Delft University of Technology (The Netherlands). His primary research interests are in the application of catalytic methodologies—homogeneous, heterogeneous and enzymatic—in organic synthesis, particularly in relation to fine chemicals production. He developed the concepts of E factors and atom utilization for assessing the environmental impact of chemical processes.

Biocatalysis in ionic liquids

Green technology actively seeks new solvents to replace common organic solvents that present inherent toxicity and have high volatility, leading to evaporation of volatile organic compounds to the atmosphere. Over the past two decades, ionic liquids (ILs) have gained enormous attention from the scientific community, and the number of reported articles in the literature has grown exponentially. Nevertheless, IL “greenness” is often challenged, mainly due to their poor biodegradability, biocompatibility, and sustainability. An alternative to ILs are deep eutectic solvents (DES). Deep eutectic solvents are defined as a mixture of two or more components, which may be solid or liquid and that at a particular composition present a high melting point depression becoming liquids at room temperature. When the compounds that constitute the DES are primary metabolites, namely, aminoacids, organic acids, sugars, or choline derivatives, the DES are so called natural deep eutectic solvents (NADES). NADES fully represen...

Natural Deep Eutectic Solvents – Solvents for the 21st Century

Environmental fate and toxicity of ionic liquids: a review.

The existing studies of the Azores triple junction, although based on specific geological or geophysical data, largely rely upon morphological considerations. However, there is no systematic bathymetric coverage of this area, and the quality of the available bathymetric charts does not allow consistent morpho-structural analysis. In this work we present a new bathymetric grid elaborated with all the available data sources in an area comprised between 24° W to 32° W and 36° N to 41° N. The basic data set corresponds to the merge of NGDC data with new swath profiles. This new map, included as an Appendix, combined with other results from seismology and neotectonics, is the basis for the study of the morpho-structural pattern of the Azores area, the present day stress field and its implications on the current view of the Azores geodynamics. As a major result, we conclude that the Azores region is controlled by two sets of conjugated faults with 120° and 150° strikes that establish the framework for the onset of volcanism, expressing as linear volcanic ridges or as point source volcanism. This interaction develops what can be considered as the morphological signature of the Azores Spreading axis segmentation. We argue that the Azores domain, presently in a broad transtensional regime, is acting simultaneously as a ultra slow spreading centre and as a transfer zone between the MAR and the dextral Gloria Fault, as it accommodates the differential shear movement between the Eurasian and African plates.

Morpho-tectonic analysis of the Azores Volcanic Plateau from a new bathymetric compilation of the area

https://www.rsc.org/suppdata/gc/b3/b303408a/b303408a.pdf

Synthesis and properties of tetra-alkyl-dimethylguanidinium salts as a potential new generation of ionic liquids

https://digital.csic.es/bitstream/10261/17760/1/Terrinha_et_al_2009.pdf

Morphotectonics and strain partitioning at the Iberia-Africa plate boundary from multibeam and seismic reflection data

/pdf/atlantic-lava-lakes-and-hot-vents-xnfypxur7r.pdf

Nuno Lourenço

Papers

Morpho-tectonic analysis of the Azores Volcanic Plateau from a new bathymetric compilation of the area

Synthesis and properties of tetra-alkyl-dimethylguanidinium salts as a potential new generation of ionic liquids

Morphotectonics and strain partitioning at the Iberia-Africa plate boundary from multibeam and seismic reflection data

Atlantic lava lakes and hot vents

Toxicological Evaluation of Ionic Liquids: Effect of Ionic Liquids on Human Colon Carcinoma HT-29 and CaCo-2 Cell Lines