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Nuno Vale
Researcher at University of Porto
Publications - 187
Citations - 3581
Nuno Vale is an academic researcher from University of Porto. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 28, co-authored 129 publications receiving 2517 citations. Previous affiliations of Nuno Vale include University of Lisbon & University of North Texas.
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Primaquine revisited six decades after its discovery.
TL;DR: Presently, aablaquine and tafenoquine the two most promising primaquine analogues are already in the final stages of clinical trials against Plasmodium vivax and P. falciparum, a new hope against malaria and other primquine-sensitive illnesses, such as Pneumocystis Pneumonia or the Chagas disease.
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Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.
Nuno Vale,Maria João Gouveia,Gabriel Rinaldi,Paul J. Brindley,Fátima Gärtner,Fátima Gärtner,José Manuel Correia da Costa,José Manuel Correia da Costa +7 more
TL;DR: Reports from the 1970s to the present are reviewed on the metabolism and mechanism of action of PZQ and its derivatives against schistosomes, which portends the selection of drug-resistant forms of these pathogens.
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Phenolic Profiling of Portuguese Propolis by LC–MS Spectrometry: Uncommon Propolis Rich in Flavonoid Glycosides
Soraia Falcão,Soraia Falcão,Nuno Vale,Paula Gomes,Maria Rosário Domingues,Cristina Freire,Susana M. Cardoso,Miguel Vilas-Boas +7 more
TL;DR: The method allowed the establishment of the phenolic profile of Portuguese propolis from different geographical locations, and the possibility to use some phenolic compounds, such as kaempferol-dimethylether, as geographical markers.
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Combination of Cell-Penetrating Peptides with Nanoparticles for Therapeutic Application: A Review
TL;DR: This review addresses the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.