O
Oguzhan Akgun
Researcher at Uludağ University
Publications - 11
Citations - 68
Oguzhan Akgun is an academic researcher from Uludağ University. The author has contributed to research in topics: Apoptosis & Chemistry. The author has an hindex of 3, co-authored 5 publications receiving 29 citations.
Papers
More filters
Journal ArticleDOI
Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9,10-anthracenedione as new anticancer agents.
Maryna Stasevych,Viktor Zvarych,V. V. Lunin,Nahide Gulsah Deniz,Zeliha Gökmen,Oguzhan Akgun,Engin Ulukaya,Vladimir Poroikov,Tatyana A. Gloriozova,Volodymyr Novikov +9 more
TL;DR: Anticancer activity predicted by PASS with a probability Pa > 30% was confirmed by the experiment and relatively small Pa values estimated by PASS indicated the novelty of the considered derivatives comparing to the compounds from the PASS training set.
Journal ArticleDOI
Mitochondrial miRNAs (MitomiRs): Their Potential Roles in Breast and Other Cancers.
TL;DR: In this paper , a review of miRNA biogenesis, transport pathways to mitochondria, and summarize mitomiRs that have been shown to play an important role in mitochondrial function, especially in the initiation and progression of breast cancer.
Journal ArticleDOI
Effective and new potent drug combination: Histone deacetylase and Wnt/β‐catenin pathway inhibitors in lung carcinoma cells
TL;DR: In this paper, the effects of combination valproic acid and niclosamide on cell viability were determined by sulforhodamine B and adenosine 5'-triphosphate viability assays.
Journal ArticleDOI
Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage.
TL;DR: Thymoquinone was shown to be the best protectant antioxidant among other antioxidants against the formation of oxidative DNA damage, whereas water-methanol extract of thyme was the best among the plant-sourced samples.
Journal ArticleDOI
Epigenetic modulators combination with chemotherapy in breast cancer cells
TL;DR: In this paper, the differential effects of standard chemotherapy regimens (FEC: 5-fluorouracil plus epirubicine plus cyclophosphamide) in combination with epigenetic modulators (decitabine, valproic acid): (a) on gene methylation levels of selected tumour biomarkers, (b) their expression status (uPA and PAI-1); (c) differentiation status (5meC and H3K27me3).