O
Oktay Uzun
Researcher at Wyss Institute for Biologically Inspired Engineering
Publications - 37
Citations - 3509
Oktay Uzun is an academic researcher from Wyss Institute for Biologically Inspired Engineering. The author has contributed to research in topics: Nanoparticle & Polymer. The author has an hindex of 23, co-authored 36 publications receiving 3178 citations. Previous affiliations of Oktay Uzun include University of Massachusetts Amherst & Massachusetts Institute of Technology.
Papers
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Journal ArticleDOI
Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles
Ayush Verma,Oktay Uzun,Yuhua Hu,Ying Hu,Hee-Sun Han,Nicki Watson,Suelin Chen,Darrell J. Irvine,Francesco Stellacci +8 more
TL;DR: It is shown that the former particles penetrate the plasma membrane without bilayer disruption, whereas the latter are mostly trapped in endosomes, offering a paradigm for analysing the fundamental problem of cell-membrane-penetrating bio- and macro-molecules.
Journal ArticleDOI
Divalent Metal Nanoparticles
Gretchen A. DeVries,Markus Brunnbauer,Ying Hu,Alicia M. Jackson,Brenda Long,Brian Neltner,Oktay Uzun,Benjamin H. Wunsch,Francesco Stellacci +8 more
TL;DR: A simple method to place target molecules specifically at two diametrically opposed positions in the molecular coating of metal nanoparticles, based on the functionalization of the polar singularities that must form when a curved surface is coated with ordered monolayers, such as a phase-separated mixture of ligands.
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Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery
Angelo S. Mao,Angelo S. Mao,Jae-Won Shin,Jae-Won Shin,Jae-Won Shin,Stefanie Utech,Huanan Wang,Huanan Wang,Oktay Uzun,Oktay Uzun,Weiwei Li,Weiwei Li,Madeline H. Cooper,Yuebi Hu,Liyuan Zhang,David A. Weitz,David A. Weitz,David J. Mooney,David J. Mooney +18 more
TL;DR: A microfluidic-based method for encapsulating single cells in a ~6 micron layer of alginate that increases the proportion of cell-containing microgels by 10-fold, with encapsulation efficiencies over 90%.
Journal ArticleDOI
Stability of Surface-Immobilized Lubricant Interfaces under Flow
Caitlin Howell,Caitlin Howell,Thy L. Vu,Thy L. Vu,Chris Johnson,Xu Hou,Xu Hou,Onyemaechi Ahanotu,Jack Alvarenga,Daniel C. Leslie,Oktay Uzun,Anna Waterhouse,Anna Waterhouse,Philseok Kim,Michael Super,Michael Super,Michael Super,Michael Aizenberg,Donald E. Ingber,Joanna Aizenberg,Joanna Aizenberg +20 more
TL;DR: In this article, the authors investigate the effects of surface type (nanostructured versus flat), surface type, and flow rate on the stability and longevity of surface-stabilized lubricant layers.
Journal ArticleDOI
Chains of Superparamagnetic Nanoparticles
TL;DR: Molecularly linked gamma-Fe2O3 nanoparticles chains arc produced from superparamagnetic gamma Fe2O 3 nanoparticles under zero applied magnetic field The chains exhibit ferromagnetic interaction between gamma Fe 2O3 particles that compose them as evidenced by an increase in blocking temperature from similar to 80 K in the case of isolated nanoparticles to similar to 120 K for chains as discussed by the authors.