O
Olivier Seksek
Researcher at Centre national de la recherche scientifique
Publications - 45
Citations - 2592
Olivier Seksek is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Intracellular & Cell culture. The author has an hindex of 16, co-authored 44 publications receiving 2425 citations. Previous affiliations of Olivier Seksek include Université Paris-Saclay & Paris Diderot University.
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Journal ArticleDOI
Size-dependent DNA Mobility in Cytoplasm and Nucleus
Gergely L. Lukacs,Peter M. Haggie,Olivier Seksek,Delphine Lechardeur,Neal D. Freedman,Alan S. Verkman +5 more
TL;DR: The results suggest that the highly restricted diffusion of DNA fragments in nucleoplasm results from extensive binding to immobile obstacles and that the decreased lateral mobility of DNAs >250 bp in cytoplasm is because of molecular crowding.
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Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus.
TL;DR: Results indicate relatively free and rapid diffusion of macromolecule-sized solutes up to approximately 500 kD in cytoplasm and nucleus.
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Chains of magnetosomes extracted from AMB-1 magnetotactic bacteria for application in alternative magnetic field cancer therapy.
Edouard Alphandéry,Stéphanie Faure,Olivier Seksek,François Guyot,François Guyot,Imène Chebbi +5 more
TL;DR: The antitumoral activity of the extracted chains of magnetosomes is demonstrated further by showing that they can be used to fully eradicate a tumor xenografted under the skin of a mouse and the higher efficiency of the extracts compared with various other materials is attributed to three factors.
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Direct measurement of trans-Golgi pH in living cells and regulation by second messengers.
TL;DR: These results provide the first direct measurement of trans-Golgi pH in living cells and demonstrate pH regulation by second messengers.
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Nuclear pH gradient in mammalian cells revealed by laser microspectrofluorimetry.
Olivier Seksek,Jacques Bolard +1 more
TL;DR: It is concluded that the nuclear membrane of these cells presents a permeability barrier to H+.