O
Omar Elfeky
Researcher at Royal Brisbane and Women's Hospital
Publications - 12
Citations - 1311
Omar Elfeky is an academic researcher from Royal Brisbane and Women's Hospital. The author has contributed to research in topics: Microvesicles & Oxygen tension. The author has an hindex of 8, co-authored 11 publications receiving 665 citations. Previous affiliations of Omar Elfeky include University of Queensland.
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Journal ArticleDOI
Association between insulin resistance and the development of cardiovascular disease
Valeska Ormazabal,Soumyalekshmi Nair,Omar Elfeky,Claudio Aguayo,Carlos Salomon,Carlos Salomon,Carlos Salomon,Felipe Zuñiga +7 more
TL;DR: It can be concluded that insulin resistance in the myocardium generates damage by at least three different mechanisms: (1) signal transduction alteration, (2) impaired regulation of substrate metabolism, and (3) altered delivery of substrates to theMyocardium.
Journal ArticleDOI
Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells-liquid biopsies for monitoring complications of pregnancy
Grace Truong,Dominic Guanzon,Vyjayanthi Kinhal,Omar Elfeky,Andrew Lai,Sherri Longo,Zarin Nuzhat,Carlos Palma,Katherin Scholz-Romero,Ramkumar Menon,Ben W.J. Mol,Gregory E. Rice,Gregory E. Rice,Carlos Salomon,Carlos Salomon +14 more
TL;DR: It is suggested that aberrant exosomal signalling by placental cells is a common aetiological factor in pregnancy complications characterised by incomplete SpA remodeling and is therefore a clinically relevant biomarker of pregnancy complications.
Journal ArticleDOI
Human placental exosomes in gestational diabetes mellitus carry a specific set of miRNAs associated with skeletal muscle insulin sensitivity.
Soumyalekshmi Nair,Nanthini Jayabalan,Dominic Guanzon,Carlos Palma,Katherin Scholz-Romero,Katherin Scholz-Romero,Omar Elfeky,Felipe Zuñiga,Valeska Ormazabal,Emilio Diaz,Gregory E. Rice,Gregory Duncombe,Thomas Jansson,Harold David McIntyre,Martha Lappas,Carlos Salomon,Carlos Salomon +16 more
TL;DR: Placental exosomes might have a role in the changes on insulin sensitivity in normal and GDM pregnancies, and the expression of these miRNAs varied in a consistent pattern in the placenta, in circulating exosome, and in skeletal muscle in GDM.
Journal ArticleDOI
Influence of maternal BMI on the exosomal profile during gestation and their role on maternal systemic inflammation.
Omar Elfeky,Sherri Longo,Andrew Lai,Gregory E. Rice,Gregory E. Rice,Carlos Salomon,Carlos Salomon +6 more
TL;DR: It is established that maternal BMI is a factor that explains a significant component of the variation in the exosomes data and may contribute to the maternal systemic inflammation during pregnancy.
Journal ArticleDOI
Review: Fetal-maternal communication via extracellular vesicles - Implications for complications of pregnancies.
Stefanie Adam,Omar Elfeky,Vyjayanthi Kinhal,Suchismita Dutta,Andrew Lai,Nanthini Jayabalan,Zarin Nuzhat,Carlos Palma,Gregory E. Rice,Carlos Salomon +9 more
TL;DR: The role of EVs during fetal-maternal communication during gestation with a special emphasis on exosomes is discussed, which has been found to be regulated by oxygen tension and glucose concentration.