O
Osamu Ogawa
Researcher at Kyoto University
Publications - 754
Citations - 21450
Osamu Ogawa is an academic researcher from Kyoto University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 70, co-authored 738 publications receiving 19302 citations. Previous affiliations of Osamu Ogawa include University of Pittsburgh & Boston Children's Hospital.
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Journal ArticleDOI
Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
Osamu Ogawa,Michael R. Eccles,Jenny Szeto,Leslie A. McNoe,Kankatsu Yun,Marion A. Maw,Peter J. Smith,Anthony E. Reeve +7 more
TL;DR: The IGF2 gene is expressed from the paternal allele in human fetal tissue, but that in Wilms' tumour expression can occur biallelically, providing the first evidence that relaxation of imprinting may play a role in the onset of disease.
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Gene Expression Levels and Immunolocalization of Organic Ion Transporters in the Human Kidney
Hideyuki Motohashi,Yuji Sakurai,Hideyuki Saito,Satohiro Masuda,Yumiko Urakami,Maki Goto,Atsushi Fukatsu,Osamu Ogawa,Ken-ichi Inui +8 more
TL;DR: Results suggest that hOOAT1, hOAT3, and hOCT2 play predominant roles in the transport of organic ions across the basolateral membrane of human proximal tubules.
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Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.
Masao Doi,Yukari Takahashi,Rie Komatsu,Fumiyoshi Yamazaki,Hiroyuki Yamada,Shogo Haraguchi,Noriaki Emoto,Yasushi Okuno,Gozoh Tsujimoto,Akihiro Kanematsu,Osamu Ogawa,Takeshi Todo,Kazuyoshi Tsutsui,Gijsbertus T. J. van der Horst,Hitoshi Okamura +14 more
TL;DR: Type VI 3β-hydroxyl-steroid dehydrogenase (Hsd3b6) is identified as a new hypertension risk factor in mice and placed in a pivotal position through which circadian clock malfunction is coupled to the development of hypertension.
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Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H+-organic cation antiporters
TL;DR: HMATE1 and hMATE2-K function together as a detoxication system, by mediating the tubular secretion of intracellular ionic compounds across the brush-border membranes of the kidney.
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Identification and Functional Characterization of a New Human Kidney–Specific H+/Organic Cation Antiporter, Kidney-Specific Multidrug and Toxin Extrusion 2
Satohiro Masuda,Tomohiro Terada,Atsushi Yonezawa,Yuko Tanihara,Koshiro Kishimoto,Toshiya Katsura,Osamu Ogawa,Ken-ichi Inui +7 more
TL;DR: Results indicate that hMATE2-K is a new human kidney-specific H+/organic cation antiporter that is responsible for the tubular secretion of cationic drugs across the brush border membranes.