O
Ott Scheler
Researcher at Tallinn University of Technology
Publications - 39
Citations - 840
Ott Scheler is an academic researcher from Tallinn University of Technology. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 10, co-authored 29 publications receiving 507 citations. Previous affiliations of Ott Scheler include Polish Academy of Sciences & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Droplet microfluidics for microbiology: techniques, applications and challenges
TL;DR: Applications of droplet microfluidics in various fields of microbiology are presented: i) detection and identification of pathogens, ii) antibiotic susceptibility testing, iii) studies of microbial physiology and iv) biotechnological selection and improvement of strains.
Journal ArticleDOI
Label-free, multiplexed detection of bacterial tmRNA using silicon photonic microring resonators
Ott Scheler,Ott Scheler,Jared T. Kindt,Abraham J. Qavi,Lauris Kaplinski,Barry Glynn,Thomas Barry,Ants Kurg,Ryan C. Bailey +8 more
TL;DR: The sensitivity of the biosensing platform allowed for detection down to 53 fmol of Streptococcus pneumoniae tmRNA, equivalent to approximately 3.16×10(7) CFU of bacteria.
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Understanding How Microorganisms Respond to Acid pH Is Central to Their Control and Successful Exploitation
Peter A. Lund,Daniela De Biase,Oded Liran,Ott Scheler,Nuno P. Mira,Zeynep Cetecioglu,Estefania Noriega Fernandez,Sara Bover-Cid,Rebecca A. Hall,Michael Sauer,Conor P. O'Byrne +10 more
TL;DR: The key molecular mechanisms known to be important for microbial survival during acid stress are surveyed and how this knowledge might be relevant to microbe-based applications and processes that are consequential for humans are discussed.
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Recent developments of microfluidics as a tool for biotechnology and microbiology.
TL;DR: A variety of biological experiments recently performed in microfluidic assays are reviewed and the key role they play in the biological experiments as: (i) controlled reaction chambers, (ii) high-throughput arrays, or (iii) micro-positioning systems are classified.
Journal ArticleDOI
Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population.
Ott Scheler,Ott Scheler,Ott Scheler,Karol Makuch,Karol Makuch,Pawel R. Debski,Michał Horka,Artur Ruszczak,Natalia Pacocha,Krzysztof Sozanski,Olli-Pekka Smolander,Witold Postek,Piotr Garstecki +12 more
TL;DR: It is found that antibiotic efficacy is determined by the amount of antibiotic used per bacterial colony forming unit (CFU), not by the absolute antibiotic concentration, as shown by the treatment of beta-lactamase-carrying Escherichia coli with cefotaxime.