P
P. Alfonsi
Researcher at University of Louisville
Publications - 11
Citations - 1031
P. Alfonsi is an academic researcher from University of Louisville. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 3 publications receiving 921 citations.
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Journal ArticleDOI
Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement.
Bruno Guignard,Anne Elisabeth Bossard,Carole Coste,Daniel I. Sessler,C. Lebrault,P. Alfonsi,Dominique Fletcher,Marcel Chauvin +7 more
TL;DR: Relatively large-dose intraoperative remifentanil increased postoperative pain and morphine consumption is suggested to have caused acute opioid tolerance and hyperalgesia.
Journal ArticleDOI
Nefopam and Ketamine Comparably Enhance Postoperative Analgesia
TL;DR: Tachycardia and profuse sweating were more frequent in patients given nefopam, and sedation was more intense with ketamine; however, the incidence of other potential complications did not differ among groups.
letters-and-commentsDOI
Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
Philip J. Devereaux,Maura Marcucci,Thomas Painter,David Cohen,Vladimir V. Lomivorotov,Daniel I. Sessler,Flávia Kessler Borges,Maria José Martinez-Zapata,Chew Yin Wang,Denis Xavier,Sandra N Ofori,Michael Ke Wang,Sergey M. Efremov,Giovanni Landoni,Ydo V. Kleinlugtenbelt,Wojciech Szczeklik,Denis Schmartz,Amit X. Garg,Timothy G. Short,Maria Wittmann,Christian S. Meyhoff,Mohammed Amir,David Torres,Ameen Patel,Emmanuelle Duceppe,Kurt Ruetzler,Joel L. Parlow,Vikas Tandon,Edith Fleischmann,Carisi Anne Polanczyk,Andre Lamy,S. V. Astrakov,Mangala Rao,William K.K. Wu,K. Bhatt,Miriam de Nadal,Valery Likhvantsev,Pilar Paniagua,Héctor J. Aguado,Richard P. Whitlock,Michael McGillion,Michael Prystajecky,Jessica Vincent,John W. Eikelboom,Ingrid Copland,Kumar Balasubramanian,Alparslan Turan,Shrikant I. Bangdiwala,David Stillo,Peter L. Gross,Teresa Cafaro,P. Alfonsi,Pavel S Roshanov,Emilie P. Belley-Côté,Jessica Spence,Toby Richards,Tomas VanHelder,William L. McIntyre,Gordon H. Guyatt,Salim Yusuf,Kate Leslie +60 more
TL;DR: Among patients undergoing noncardiac surgery, the incidence of the composite bleeding outcome was significantly lower with tranexamic acid than with placebo, and the between-group difference in the composite cardiovascular outcome was small, the noninferiority of tranxamic acid was not established.
Journal ArticleDOI
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery
Maura Marcucci,Thomas Painter,David Cohen,Kate Leslie,Vladimir V. Lomivorotov,Daniel I. Sessler,Flávia Kessler Borges,M. J. Martínez Zapata,C. Y. Wang,Denis Xavier,Sandra N Ofori,Giovanni Landoni,Sergey M. Efremov,Ydo V. Kleinlugtenbelt,Wojciech Szczeklik,Denis Schmartz,Amit X. Garg,Timothy G. Short,Maria Wittmann,Christian S. Meyhoff,Mohammed Amir,David Torres,Ameen Patel,Emmanuelle Duceppe,Kurt Ruetzler,Joel L. Parlow,Vikas Tandon,Michael Ke Wang,Edith Fleischmann,Carisi Anne Polanczyk,Raja Jayaram,S. V. Astrakov,Mangala Rao,Tomas VanHelder,William K.K. Wu,Chao Chia Cheong,Sabry Ayad,Marat N Abubakirov,Mikhail Y. Kirov,K. Bhatt,Miriam de Nadal,Valery Likhvantsev,Pilar Paniagua Iglesisas,Héctor J. Aguado,Michael McGillion,Andre Lamy,Richard P. Whitlock,Pavel S Roshanov,David Stillo,Ingrid Copland,Jessica Vincent,Kumar Balasubramanian,Shrikant I. Bangdiwala,Bruce M Biccard,Andrea Kurz,Sadeesh Srinathan,Shirley Petit,John W. Eikelboom,Toby Richards,Peter L. Gross,P. Alfonsi,Gordon H. Guyatt,E. Belley-Côté,Jessica Spence,William L. McIntyre,Salim Yusuf,Philip J. Devereaux +66 more
TL;DR: The PeriOperative Ischemic Evaluation (POISE)-3 Trial as mentioned in this paper was designed to determine if tranexamic acid (TXA) is superior to placebo for the composite outcome of life-threatening, major, and critical organ bleeding, and non-inferior to the placebo for occurrence of major arterial and venous thrombotic events, at 30 days after randomization.
Journal ArticleDOI
Acute urinary retention and urinary tract infection after short‐course urinary drainage in colon or high rectum anastomoses: Post hoc analysis of a multicentre prospective database from the GRACE group
A. Venara,J. Hamel,Jean-Marc Regimbeau,Julien Gillet,Jean Joris,Eddy Cotte,Karem Slim,Orabi Nora Abbes,Elodie Agut,P. Alfonsi,Asma Alili,Jibba Amraoui,Adeline Andre,Jean‐Marc Arimon,Laurent Arnalsteen,Robert Asztalos,Cyril Audouy,Ophélie Aumont,Sylvain Auvray,Hubert Baietto,Gregorio Balbo,Maryse Barreau Aguilera,Nathan Beaupel,Zeineb Ben Lazreg,S. Beguinot‐Holtzscherer,Jean‐Paul Beller,A. Bellouard,Imed Ben Henda,Mohamed Bentamene,Pierre Bernard,Nicolas Berthon,Amélie Biblocque,Thomas Bièvre,M. Bilosi,Benjamin Blanc,S. Blaye‐Felice,Adrien Blatt,D. Blehaut,Anne-Florence Bock,Jean-Pierre Bongiovanni,Marc Bonnet,Noredinne Bouarroudj,David Boissier,Henry Boret,Ruddy Borg,Zoheir Bouchair,François Bouchard,M. Boumadani,D. Bounicaud,O. Bourdeix,J. C. Bourseau,Guillaume Bozio,Dorothée Brachet,Amine Brek,N. Briez,C. Buisset‐Subiran,Brigitte Calvet,Anna Cartaux‐Taieb,Mariela Castiglioni,Maryline Catinois,Mael Chalret du Rieu,Claire Chalumeau,G. Chambrier,Reza Chamlou,Nathalie Chapel,P. Y. Chenet,Pierre Chirac,Seddik Chokkairi,X. Chopin,Niki Christou,Etienne Chuffart,François Corfiotti,C. Craus,E. Cuellar,Gilles Dardenne,Nicola de’Angelis,Ugo de Ioro,Fabien Dechanet,Rachel Dellis,Laurence Demasles,Christine Denet,Benjamin Deroo,Véronique Desfourneaux‐Denis,Sylvain Dileon,Richard Douard,C.Casquero Dorado,E Dorscheid,Frédéric Dumont,F Duramé,Emilie Duchalais,Aurélien Dupré,S. Dufraisse,Mohamed Amine Elghali,Emmeric Hutin,Aloui Emna,Eric Essome,N. Fabre,Virginie Faivre,Jean-Luc Faucheron,P Favoulet,Philippe Fernou,O. Firtion,Renaud Flamein,Sabina Florea,C. De la Fontaine,Damien Forestier,Erwan Fourn,Dacian Vasile Frentiu,R Frisoni,A. Frisoni,Thomas Gautier,Florent Genty,Sebastian Georgeanu,Adeline Germain,Stephanie Gibert,Bruno Gilbert,Benoit Gignoux,Nicolas Goasguen,Pierre Goubault,Philippe Grès,Jeremie Guedj,Bruno Guignard,Jean Gugenheim,C. Guaquiere,José Guiot,D. Guinier,K. Hail,Caroline Hatwel,Elean Iatan,Thérèse Janecki,T. Jany,Jerome Jaspart,Frédéric Journe,Lionel Jouffret,Aicha Kassoul,Fehmi Kattou,Philip Keller,T. Knepfler,Tarik Khouri,K. Kothonidis,Pierre Landreau,Guillaume Langlois,G. Le Bartz,Sébastien Lebas,Daniel Léonard,David Leonard,J Leporrier,G. Lescure,Romain Lewandowski,Antonella Di Liddo,Jean‐Hugues Longeville,Ioan Lucescu,A. Mariani,Pascale Mariani,Gwenaëlle Martin,Olivier Martinet,Damien Massalou,Jean‐Loup Massard,François Mauvais,D. Mazza,Jean Mbuyamba Katapile,F. Milou,F. Mirre,C. Mor-Martinez,Alexandre Mensier,C. Mergui,Jean-Phillippe Mestrallet,Caroline Meyer,Nicolas Mocellin,Serge Montagne,O. Naseef,Marion Orville,Sandrine Ostermann‐Bucher,Mehdi Ouaissi,Xavier Paqueron,Cyrielle Paquet,L. Passebois,Virginie Pichot-Delahaye,Marc Pillet,J. C. Pottie,Laurent Plard,F. Plumereau,James Poincenot,Marie Poisblanc,B. Poupard,J. M. Proske,Pierre Puche,O. Raspado,Romain Riboud,Barivola Rakotoarisoa,K. Raynaud,Thierry Razafindratsira,Myriam Renaud,D. F. Rio,J. Ripoche,Benjamin Roussel,Marc Saint Denis,Pascale Salaun,P.-Y. Sage,M.-L. Scherrer,Franck Sirisier,Boudewijn J. J. Smeets,M. Smejkal,J P Steinmetz,Marion Tavernier,Remy Thievenaz,Mihaela Tirca,Laurence Toqué,Elhocine Triki,D. Tzanis,Bernard Vacher,Serge Vanwymeersch,Estelle Vauclair,Romain Verhaeghe,V. Vetrila,Christine Vieuille,F. Vermeulen,J. Vignal,C. Voilin,Pierre de Wailli,Albert Wolthuis,Sophie Zaepfel +221 more
TL;DR: The aim was to define the risk factors for acute urinary retention (AUR) and urinary tract infections (UTIs) in colon or high rectum anastomosis patients based on the absence of a urinary catheter or the early removal of the UC.