R
Richard P. Whitlock
Researcher at Population Health Research Institute
Publications - 333
Citations - 11983
Richard P. Whitlock is an academic researcher from Population Health Research Institute. The author has contributed to research in topics: Medicine & Randomized controlled trial. The author has an hindex of 46, co-authored 273 publications receiving 9255 citations. Previous affiliations of Richard P. Whitlock include Hamilton Health Sciences & University of Mississippi Medical Center.
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Journal ArticleDOI
Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes
Fernando Botto,Pablo Alonso-Coello,Matthew T. V. Chan,Matthew T. V. Chan,Juan Carlos Villar,Denis Xavier,Sadeesh Srinathan,Gordon H. Guyatt,Patricia Cruz,Patricia Cruz,Michelle M. Graham,Michelle M. Graham,Chew Yin Wang,Otavio Berwanger,R.M. Pearse,R.M. Pearse,Bruce M Biccard,Valsa Abraham,Germán Málaga,Germán Málaga,Graham S. Hillis,Graham S. Hillis,Reitze N. Rodseth,Deborah J. Cook,Deborah J. Cook,Deborah J. Cook,Carisi Anne Polanczyk,Wojciech Szczeklik,Daniel I. Sessler,Daniel I. Sessler,Tej Sheth,Tej Sheth,Gareth L Ackland,Gareth L Ackland,Martin Leuwer,Amit X Garg,Amit X Garg,Yannick LeManach,Yannick LeManach,Shirley Pettit,Diane Heels-Ansdell,Giovanna Luratibuse,Giovanna Luratibuse,Michael Walsh,Michael Walsh,Robert Sapsford,Holger J Schünemann,Holger J Schünemann,Andrea Kurz,Andrea Kurz,Sabu Thomas,Marko Mrkobrada,Marko Mrkobrada,Lehana Thabane,Hertzel C. Gerstein,Pilar Paniagua,Pilar Paniagua,Peter Nagele,Peter Nagele,Parminder Raina,Salim Yusuf,Salim Yusuf,Salim Yusuf,Philip J. Devereaux,Philip J. Devereaux,Matthew J. McQueen,Mohit Bhandari,Jackie Bosch,Norman Buckley,Clara K Chow,Richard Halliwell,Stephen Li,Vincent W. Lee,J. Mooney,Mariana Vargas Furtado,Erica Aranha Suzumura,Eliana Vieira Santucci,Katia R. M. Leite,Jose Amalth do Espirirto Santo,César A. Jardim,Alexandre Biasi Cavalcanti,Hélio Penna Guimarães,Michael J Jacka,Finlay A. McAlister,Sean McMurtry,Derek R. Townsend,Neesh Pannu,Sean M. Bagshaw,Amal Bessissow,Emmanuelle Duceppe,John W. Eikelboom,Javier Ganame,James Hankinson,Stephen Hill,Sanjit S. Jolly,Andre Lamy,Elizabeth Ling,Patrick Magloire,Guillaume Paré,Deven Reddy,David Szalay,Jacques G. Tittley,Jeff Weitz,Richard P. Whitlock,Saeed Darvish-Kazim,Justin DeBeer,Peter A. Kavsak,Clive Kearon,Richard Mizera,Martin O'Donnell,Matthew B. McQueen,Jehonathan H. Pinthus,Sebastian Ribas,Marko Simunovic,Vikas Tandon,Tomas VanHelder,Mitchell Winemaker,Sarah D. McDonald,Paul M. O'Bryne,Ameen Patel,James Paul,Zubin Punthakee,Karen Raymer,Omid Salehian,Frederick A. Spencer,Stephen D. Walter,Andrew Worster,Anthony Adili,Catherine M. Clase,Mark Crowther,James D. Douketis,Azim S. Gangji,Paul Jackson,Wendy Lim,Peter Lovrics,Sergio Mazzadi,William Orovan,Jill Rudkowski,Mark Soth,Maria Tiboni,Rey R. Acedillo,Amit Garg,Amit Garg,Ainslie Hildebrand,Ngan N. Lam,Danielle MacNeil,Pavel S Roshanov,Sadeesh K Srinathan,Clare D. Ramsey,Philip St John,Laurel Thorlacius,Faisal Siddiqui,Hilary P Grocott,Andrew McKay,Trevor W R Lee,Ryan J. J. Amadeo,Duane J. Funk,Heather McDonald,James Zacharias,Olga L. Cortés,Maria Stella Chaparro,Skarlett Vásquez,Alvaro Castañeda,Silvia Moreira Ayub Ferreira,Pierre Coriat,Denis Monneret,Jean Pierre Goarin,Cristina Ibanez Esteve,Catherine Royer,Georges Daas,Gordon Y.S. Choi,Tony Gin,Lydia C.W. Lit,Alben Sigamani,Atiya Faruqui,Radhika Dhanpal,Smitha Almeida,Joseph Cherian,Sultana Furruqh,Lalita Afzal,P. George,Shaveta Mala,Holger Schünemann,Holger Schünemann,Paola Muti,Enrico Vizza,Gracie Ong,Marzida Mansor,Alvin S.B. Tan,Ina Ismiarti Shariffuddin,V Vasanthan,Noorjahan Haneem Md Hashim,A. Wahab Undok,Ushananthini Ki,Hou Yee Lai,Wan Azman Ahmad,Azad Hassan Abdul Razack,Vanessa Valderrama-Victoria,Javier D Loza-Herrera,Maria De Los Angeles Lazo,Aida Rotta-Rotta,Barbara Sokołowska,Jacek Musial,Jacek Górka,Paweł Iwaszczuk,Mateusz Kózka,Maciej Chwała,Marcin Raczek,Tomasz Mrowiecki,Bogusz Kaczmarek,B M Biccard,Hussein Cassimjee,Dean Gopalan,Theroshnie Kisten,Aine Mugabi,P. Naidoo,Rubeshan Naidoo,R.N. Rodseth,D.L. Skinner,Alex Torborg,Gerard Urrútia,Mari Luz Maestre,Miquel Santaló,Raúl Gonzalez,Adrià Font,Cecilia Martínez,Xavier Pelaez,Marta De Antonio,José Villamor,Jesús Alvarez García,Maria José Ferré,Ekaterina Popova,Ignacio Garutti,Carmen Fernández,Maria Palencia,Susana Díaz,Teresa Del Castillo,Alberto Varela,Angeles de Miguel,Manuel Muñoz,Patricia Piñeiro,Gabriel Cusati,Maria Del Barrio,Maria José Membrillo,David Orozco,Fidel Reyes,Robert J. Sapsford,Julian H. Barth,Julian Scott,Alistair Hall,Simon J. Howell,Michaela Lobley,Janet Woods,Susannah Howard,Joanne Fletcher,Nikki Dewhirst,C. Williams,A. Rushton,Ingeborg Welters,M Leuwer,Rupert Pearse,Rupert Pearse,G.L. Ackland,G.L. Ackland,Ahsun Khan,Edyta Niebrzegowska,Sally Benton,Andrew Wragg,Andrew Archbold,Amanda Smith,Eleanor McAlees,Cheryl Ramballi,Neil MacDonald,Marta Januszewska,Robert C M Stephens,Anna Reyes,Laura Gallego Paredes,Pervez Sultan,David Cain,John Whittle,Ana Gutierrez del Arroyo,Zhuo Sun,Patrick S Finnegan,Cameron Egan,Hooman Honar,Aram Shahinyan,Krit Panjasawatwong,Alexander Y. Fu,Sihe Wang,Edmunds Reineks,Jane Blood,Megan Kalin,David W. Gibson,Troy S. Wildes,Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (Vision) Investigators +294 more
TL;DR: Among adults undergoing noncardiac surgery, MINS was an independent predictor of 30-day mortality and had the highest population-attributable risk of the perioperative complications.
Journal ArticleDOI
Aspirin in Patients Undergoing Noncardiac Surgery
Marko Mrkobrada,Marko Mrkobrada,Kate Leslie,Pablo Alonso-Coello,Andrea Kurz,Alben Sigamani,Gordon H. Guyatt,A. Robinson,F. Botto,G. Lurati Buse,G. Lurati Buse,Denis Xavier,Maria Tiboni,Deborah J. Cook,Patrice Forget,Germán Málaga,Edith Fleischmann,Mohammed Amir,John W. Eikelboom,John W. Eikelboom,Ryszard Mizera,David Torres,Tomas VanHelder,Pilar Paniagua,Otavio Berwanger,Sadeesh Srinathan,Michelle M. Graham,Laura Pasin,Y Le Manach,Y Le Manach,Peggy Gao,Janice Pogue,Janice Pogue,Richard P. Whitlock,Richard P. Whitlock,Andre Lamy,Andre Lamy,Clive Kearon,Colin Baigent,Clara K Chow,Shirley Pettit,S. Chrolavicius,Salim Yusuf,Salim Yusuf,Abstr Act,Abstr Act +45 more
TL;DR: Administration of aspirin before surgery and throughout the early postsurgical period had no significant effect on the rate of a composite of death or nonfatal myocardial infarction but increased the risk of major bleeding.
Journal ArticleDOI
Off-Pump or On-Pump Coronary-Artery Bypass Grafting at 30 Days
Andre Lamy,Dorairaj Prabhakaran,David P. Taggart,Shengshou Hu,Ernesto Paolasso,Zbynek Straka,Leopoldo S. Piegas,Ahmet Rüçhan Akar,Anil Jain,Nicolas Noiseux,Chandrasekar Padmanabhan,Juan-Carlos Bahamondes,Richard J. Novick,Prashant Vaijyanath,Sukesh Reddy,Liang Tao,Pablo A. Olavegogeascoechea,Balram Airan,Toomas-Andres Sulling,Richard P. Whitlock,Yongning Ou,Jennifer Ng,Susan Chrolavicius,Salim Yusuf +23 more
TL;DR: The use of off-pump CABG resulted in reduced rates of transfusion, reoperation for perioperative bleeding, respiratory complications, and acute kidney injury but also resulted in an increased risk of early revascularization.
Journal ArticleDOI
Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.
Philip J. Devereaux,Bruce M Biccard,Alben Sigamani,Denis Xavier,Matthew T. V. Chan,Sadeesh Srinathan,Michael Walsh,Valsa Abraham,Rupert M Pearse,Chew Yin Wang,Daniel I. Sessler,Andrea Kurz,Wojciech Szczeklik,Otavio Berwanger,Juan Carlos Villar,Germán Málaga,Amit X. Garg,Clara K Chow,Gareth L. Ackland,Ameen Patel,Flávia Kessler Borges,Emilie P. Belley-Côté,Emmanuelle Duceppe,Jessica Spence,Vikas Tandon,Colin Williams,Robert J. Sapsford,Carisi Anne Polanczyk,Maria Tiboni,Pablo Alonso-Coello,Atiya Faruqui,Diane Heels-Ansdell,Andre Lamy,Richard P. Whitlock,Yannick LeManach,Pavel S Roshanov,Michael McGillion,Peter A. Kavsak,Matthew J. McQueen,Lehana Thabane,Reitze N. Rodseth,Giovanna Lurati Buse,Mohit Bhandari,Ignacia Garutti,Michael J. Jacka,Holger J. Schünemann,Olga L. Cortés,Pierre Coriat,Nazari Dvirnik,Fernando Botto,Shirley Pettit,Allan S. Jaffe,Gordon H. Guyatt +52 more
TL;DR: Among patients undergoing noncardiac surgery, peak postoperative hsTnT during the first 3 days after surgery was significantly associated with 30-day mortality and potential diagnostic criteria for MINS was found.
Journal ArticleDOI
Antithrombotic and Thrombolytic Therapy for Valvular Disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
TL;DR: This guideline provides recommendations based on the optimal balance of thrombotic and hemorrhagic risk in valvular disease and recommends vitamin K antagonist therapy for rheumatic mitral disease and valve repair.