P
P. Meera Khan
Researcher at Leiden University
Publications - 177
Citations - 9440
P. Meera Khan is an academic researcher from Leiden University. The author has contributed to research in topics: Gene & Familial adenomatous polyposis. The author has an hindex of 42, co-authored 177 publications receiving 9339 citations. Previous affiliations of P. Meera Khan include Netherlands Cancer Institute.
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The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC).
TL;DR: The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) H. Vasen, M. Mecklin, P. Lynch, and H. Meera Khan present a meta-analysis of 125 cases of patients with central giant cell carcinoma of the colon and rectum found to have had atypical EMTs.
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Report of the committee on the genetic constitution of autosomes other than chromosomes 1,2 and 6.
Frank H. Ruddle,P. Meera Khan +1 more
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Enzyme electrophoresis on cellulose acetate gel: Zymogram patterns in man-mouse and man-Chinese hamster somatic cell hybrids
TL;DR: Techniques, developed during the course of a series of investigations on somatic cell hybrids in this laboratory, are described for the electrophoretic characterization of glycose-6-phosphate dehydrogenase, nicotinamide adenine dinucleotide phosphate-dependant isocitrate dehydrogen enzyme, and phosphoglycerate kinase 2 in the man-mouse and man-Chinese hamster somatic Cellogel systems.
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Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
Ron Smits,Menno F. Kielman,Cor Breukel,Chris Zurcher,Kristi L. Neufeld,Shantie Jagmohan-Changur,Nandy Hofland,Jaap E. van Dijk,Ray White,Winfried Edelmann,Raju Kucherlapati,P. Meera Khan,Riccardo Fodde +12 more
TL;DR: The generation of a mouse model carrying a targeted mutation at codon 1638 of the mouse Apc gene, Apc1638T, resulting in a truncated Apc protein encompassing three of the seven 20 amino acid repeats and one SAMP motif, but missing all of the carboxy-terminal domains thought to be associated with tumorigenesis is described.