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Padma Das

Researcher at Indian Institute of Chemical Biology

Publications -  14
Citations -  611

Padma Das is an academic researcher from Indian Institute of Chemical Biology. The author has contributed to research in topics: Apoptosis & Autophagy. The author has an hindex of 10, co-authored 14 publications receiving 487 citations.

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Menstrual Hygiene Practices, WASH Access and the Risk of Urogenital Infection in Women from Odisha, India

TL;DR: Interventions that ensure women have access to private facilities with water for MHM and that educate women about safer, low-cost MHM materials could reduce urogenital disease among women.
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Synthesis and biological evaluation of a novel betulinic acid derivative as an inducer of apoptosis in human colon carcinoma cells (HT-29).

TL;DR: Bio-physical studies indicate that compound 2c acts as a minor groove binder to the DNA as a promising inducer of apoptosis that follows a mitochondria dependent pathway.
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Synthesis, cytotoxicity, and structure-activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent

TL;DR: A series of analogues of andrographolide, prepared through chemo-selective functionalization at C14 hydroxy, have been evaluated for in vitro cytotoxicities against human leukemic cell lines and revealed that the α-alkylidene-γ-butyrolactone moiety of androgramolide played a major role in the activity profile.
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Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway

TL;DR: These findings prove the dual ability of AG–4 to induce apoptosis and autophagy which provide a new perspective to it as a potential molecule targeting PCD for future cancer therapeutics.
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Monitoring of intracellular nitric oxide in leishmaniasis: Its applicability in patients with visceral leishmaniasis

TL;DR: A flow cytometric approach to perform real time biological detection of NO within Leishmania parasites and parasitized macrophages using a membrane permeable derivative of diaminofluorescein diacetate is developed and provides a real time approach for monitoring the effect of anti‐leishmanial compounds.