P
Padma Das
Researcher at Indian Institute of Chemical Biology
Publications - 14
Citations - 611
Padma Das is an academic researcher from Indian Institute of Chemical Biology. The author has contributed to research in topics: Apoptosis & Autophagy. The author has an hindex of 10, co-authored 14 publications receiving 487 citations.
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Journal ArticleDOI
Menstrual Hygiene Practices, WASH Access and the Risk of Urogenital Infection in Women from Odisha, India
Padma Das,Kelly K. Baker,Ambarish Dutta,Tapoja Swain,Sunita Sahoo,Bhabani S. Das,Bijay Panda,Arati Nayak,Mary Bara,Bibiana Bilung,Pravas Ranjan Mishra,Pinaki Panigrahi,Sandy Cairncross,Belen Torondel +13 more
TL;DR: Interventions that ensure women have access to private facilities with water for MHM and that educate women about safer, low-cost MHM materials could reduce urogenital disease among women.
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Synthesis and biological evaluation of a novel betulinic acid derivative as an inducer of apoptosis in human colon carcinoma cells (HT-29).
Biswajit Chakraborty,Debasmita Dutta,Sanjukta Mukherjee,Supriya Das,Nakul C. Maiti,Padma Das,Chinmay Chowdhury +6 more
TL;DR: Bio-physical studies indicate that compound 2c acts as a minor groove binder to the DNA as a promising inducer of apoptosis that follows a mitochondria dependent pathway.
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Synthesis, cytotoxicity, and structure-activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent
Bimolendu Das,Chinmay Chowdhury,Deepak Kumar,Rupashree Sen,Rajneeta Roy,Padma Das,Mitali Chatterjee +6 more
TL;DR: A series of analogues of andrographolide, prepared through chemo-selective functionalization at C14 hydroxy, have been evaluated for in vitro cytotoxicities against human leukemic cell lines and revealed that the α-alkylidene-γ-butyrolactone moiety of androgramolide played a major role in the activity profile.
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Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway
Deepak Kumar,Bimolendu Das,Rupashree Sen,Priyanka Kundu,Alak Manna,Avijit Sarkar,Chinmay Chowdhury,Mitali Chatterjee,Padma Das +8 more
TL;DR: These findings prove the dual ability of AG–4 to induce apoptosis and autophagy which provide a new perspective to it as a potential molecule targeting PCD for future cancer therapeutics.
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Monitoring of intracellular nitric oxide in leishmaniasis: Its applicability in patients with visceral leishmaniasis
Avijit Sarkar,Piu Saha,Goutam Mandal,Debanjan Mukhopadhyay,Susmita Roy,Sunny Kumar Singh,Sukhen Das,Rama Prosad Goswami,Bibhuti Saha,Deepak Kumar,Padma Das,Mitali Chatterjee +11 more
TL;DR: A flow cytometric approach to perform real time biological detection of NO within Leishmania parasites and parasitized macrophages using a membrane permeable derivative of diaminofluorescein diacetate is developed and provides a real time approach for monitoring the effect of anti‐leishmanial compounds.