P
Palak Kathiria
Researcher at University of Lethbridge
Publications - 14
Citations - 1021
Palak Kathiria is an academic researcher from University of Lethbridge. The author has contributed to research in topics: Tobacco mosaic virus & Nicotiana tabacum. The author has an hindex of 10, co-authored 14 publications receiving 902 citations. Previous affiliations of Palak Kathiria include Agriculture and Agri-Food Canada & National Research Council.
Papers
More filters
Journal ArticleDOI
Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond.
TL;DR: The genetic and epigenetic mechanisms of MN formation after various clastogenic and aneugenic effects on cell division and cell cycle are described and individual sensitivity to MN formation due to single gene polymorphisms is discussed.
Journal ArticleDOI
Transgenerational changes in the genome stability and methylation in pathogen-infected plants (Virus-induced plant genome instability)
TL;DR: It is found that the progeny of plants that received a virus-induced systemic signal that increased the somatic and meiotic recombination rates in tobacco mosaic virus-infected tobacco plants also have a higher frequency of rearrangements in the loci carrying the homology to LRR region of the gene of resistance to TMV (N-gene).
Journal ArticleDOI
Tobacco mosaic virus infection results in an increase in recombination frequency and resistance to viral, bacterial and fungal pathogens in the progeny of infected tobacco plants
Palak Kathiria,Corinne Sidler,Andrey Golubov,Melanie Kalischuk,Lawrence M. Kawchuk,Igor Kovalchuk +5 more
TL;DR: It is reported that tobacco plants infected with TMV exhibited an increase in HRF in two consecutive generations, and viral infection triggers specific changes in progeny that promote higher levels of HRF at the transgene and higher resistance to stress as compared with the progeny of unstressed plants.
Journal ArticleDOI
Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring
Jan Tamminga,Igor Koturbash,Michael A. Baker,Kristy Kutanzi,Palak Kathiria,Igor P. Pogribny,Robert J. Sutherland,Olga Kovalchuk +7 more
TL;DR: It is reported that the localized paternal cranial irradiation results in a significant accumulation of unrepaired DNA lesions in sperm cells and leads to a profound epigenetic dysregulation in the unexposed progeny conceived a week after paternal exposure.
Journal ArticleDOI
DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation
TL;DR: It is shown that the DNA damage-induced and ATR/Rfx1-mediated increase of miR-709 expression in exposed testes may be a protective mechanism that effectively decreases a cellular level of BORIS to prevent massive aberrant erasure of DNA methylation after radiation exposure.