P
Pamela K. Burrows
Researcher at George Washington University
Publications - 26
Citations - 3106
Pamela K. Burrows is an academic researcher from George Washington University. The author has contributed to research in topics: Randomized controlled trial & Prenatal care. The author has an hindex of 15, co-authored 26 publications receiving 2643 citations.
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Journal ArticleDOI
A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele
N. Scott Adzick,Elizabeth Thom,Catherine Y. Spong,John W. Brock,Pamela K. Burrows,Mark P. Johnson,Lori J. Howell,Jody A. Farrell,Mary E. Dabrowiak,Leslie N. Sutton,Nalin Gupta,Noel Tulipan,Diana L. Farmer +12 more
TL;DR: Prenatal surgery for myelomeningocele reduced the need for shunting and improved motor outcomes at 30 months but was associated with maternal and fetal risks and increased risk of preterm delivery and uterine dehiscence at delivery.
Journal ArticleDOI
A Randomized Trial of Prenatal Versus Postnatal Repair of Myelomeningocele
N. Scott Adzick,Elizabeth Thom,Catherine Y. Spong,John W. Brock,Pamela K. Burrows,Mark P. Johnson,Lori J. Howell,Jody A. Farrell,Mary E. Dabrowiak,Leslie N. Sutton,Nalin Gupta,Noel Tulipan,Mary E. D'Alton,Diana L. Farmer +13 more
TL;DR: Myelomeningocele is one of the most common birth defects, characterized by a defect in the bony spine and resultant extrusion of the spinal cord into a sac filled with cerebrospinal fluid.
Journal ArticleDOI
A Randomized Trial of Prenatal Versus Postnatal Repair of Myelomeningocele
N. Scott Adzick,Elizabeth Thom,Catherine Y. Spong,John W. Brock,Pamela K. Burrows,Mark P. Johnson,Lori J. Howell,Jody A. Farrell,Mary E. Dabrowiak,Leslie N. Sutton,Nalin Gupta,Noel Tulipan,Mary E. D'Alton,Diana L. Farmer +13 more
TL;DR: Prenatal repair by hysterotomy may offer better neurological function than repair delayed until after delivery, but it can also increase maternal risk, including preterm labor and uterine dehiscence, and has an increased risk of fetal or neonatal death and preterm birth.
Journal ArticleDOI
Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement
Noel Tulipan,John C. Wellons,Elizabeth Thom,Nalin Gupta,Leslie N. Sutton,Pamela K. Burrows,Diana L. Farmer,William F. Walsh,Mark P. Johnson,Larry Rand,S. Tolivaisa,Mary E. D'Alton,N. S. Adzick,Lori J. Howell,A Flak,Holly Hedrick,J Koh,Jack Rychik,Natalie E. Rintoul,Julie S. Moldenhauer,R. D. Wilson,Beverly G. Coleman,David Cohen,P Pasquariello,Larissa T. Bilaniuk,Harrison Mr,Hang Lee,Jody A. Farrell,Tamara Ryan,Rachel Perry,John W. Brock,Mary E. Dabrowiak,Katharine D. Wenstrom,J Bruner,E Yang,Nancy C. Chescheir,T Perry,EG Musok,K Holloway,Catherine Y. Spong,R Higgins +40 more
TL;DR: Larger ventricles at initial screening are associated with an increased need for shunting among those undergoing fetal surgery for myelomeningocele and care should be exercised in recommending prenatal surgery when the ventricle size is 15 mm or larger because prenatal surgery does not appear to improve outcome in this group.
Journal ArticleDOI
The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes.
Diana L. Farmer,Diana L. Farmer,Elizabeth Thom,John W. Brock,Pamela K. Burrows,Mark P. Johnson,Lori J. Howell,Jody A. Farrell,Nalin Gupta,N. Scott Adzick +9 more
TL;DR: The data for the full cohort of 183 patients corroborate the original findings of Management of Myelomeningocele Study, confirming that prenatal repair improves the primary outcome composite score of mental development and motor function.