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Panagiota Golfi
Researcher at King's College London
Publications - 4
Citations - 220
Panagiota Golfi is an academic researcher from King's College London. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 4, co-authored 4 publications receiving 188 citations.
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ADAM8 as a drug target in pancreatic cancer
Uwe Schlomann,Garrit Koller,Catharina Conrad,Taheera Ferdous,Panagiota Golfi,Adolfo Molejon Garcia,Sabrina Höfling,Madeline Parsons,Patricia Costa,Robin Soper,Maud Bossard,Thorsten Hagemann,Rozita Roshani,Norbert Sewald,Randal R. Ketchem,Marcia L. Moss,Fred H. Rasmussen,Miles A. Miller,Douglas A. Lauffenburger,David A. Tuveson,Christopher Nimsky,Joerg W. Bartsch +21 more
TL;DR: The data integrate ADAM8 in pancreatic cancer signalling and validateADAM8 as a target for PDAC therapy are validated.
ADAM8 as a drug target in pancreatic cancer
Uwe Schlomann,Garrit Koller,Catharina Conrad,Taheera Ferdous,Panagiota Golfi,Adolfo Molejon Garcia,Sabrina Höfling,Maddy Parsons,Patricia Costa,Robin Soper,Maud Bossard,Thorsten Hagemann,Rozita Roshani,Norbert Sewald,Randal R. Ketchem,Marcia L. Moss,Fred H. Rasmussen,David A. Tuveson,Christopher Nimsky,Jörg W. Bartsch,Miles A. Miller,Douglas A. Lauffenburger +21 more
Journal ArticleDOI
Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: Implications for human motor neuron disease
Ralf Palmisano,Panagiota Golfi,Peter Heimann,Christopher Shaw,Claire Troakes,Thomas Schmitt-John,Joerg W. Bartsch,Joerg W. Bartsch +7 more
TL;DR: This study provides the first evidence for wobbler-like aetiologies in human ALS and suggests that the genes encoding proteins involved in vesicle trafficking should be screened for pathogenic mutations.
Journal ArticleDOI
ADAM8/MS2/CD156, an Emerging Drug Target in the Treatment of Inflammatory and Invasive Pathologies
TL;DR: As ADAM8 progressively emerges as a key effector in pathological processes, so does its attractiveness as a therapeutic target rather than being a mere indicator of disease and its progression, and it potentially is an attractive drug target in a variety of diseases.