P
Paola Borgiani
Researcher at University of Rome Tor Vergata
Publications - 141
Citations - 3126
Paola Borgiani is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 30, co-authored 130 publications receiving 2591 citations.
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Journal ArticleDOI
CYP4F2 genetic variant (rs2108622) significantly contributes to warfarin dosing variability in the Italian population.
Paola Borgiani,Cinzia Ciccacci,Vittorio Forte,Elisabetta Sirianni,L. Novelli,Placido Bramanti,Giuseppe Novelli +6 more
TL;DR: The data confirm and strengthen the role of the new CYP4F2 variant relative contribution in explaining warfarin dose variability with respect to CYP2C9 and VKORC1 genetic variants together with age and weight.
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A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics.
Clint Mizzi,Clint Mizzi,Eleni Dalabira,Judit Kumuthini,Nduna Dzimiri,Istvan Balogh,Nazli Basak,Ruwen Böhm,Joseph Borg,Paola Borgiani,Nada Bozina,Henrike Bruckmueller,Beata Burzynska,Angel Carracedo,Ingolf Cascorbi,Constantinos Deltas,Vita Dolzan,Anthony G. Fenech,Godfrey Grech,Vytautas Kasiulevičius,Ľudevít Kádaši,Ľudevít Kádaši,Vaidutis Kučinskas,Elza Khusnutdinova,Elza Khusnutdinova,Yiannis L. Loukas,Milan Macek,Halyna Makukh,Ron H.J. Mathijssen,Konstantinos Mitropoulos,Christina Mitropoulou,Giuseppe Novelli,Ioanna Papantoni,Sonja Pavlovic,Giuseppe Saglio,Jadranka Setric,Jadranka Setric,Maja Stojiljkovic,Andrew P. Stubbs,Alessio Squassina,María Dolores Torres,Marek Turnovec,Ron H.N. van Schaik,Konstantinos Voskarides,Salma M. Wakil,Anneke N. Werk,Maria Del Zompo,Branka Zukic,Theodora Katsila,Ming Ta Michael Lee,Alison Motsinger-Rief,Howard L. Mc Leod,Peter J. van der Spek,George P. Patrinos,George P. Patrinos +54 more
TL;DR: The microattribution approach is implemented to assess the pharmacogenomic biomarkers allelic spectrum in 18 European populations, mostly from developing European countries, by analyzing 1,931 pharmacogenomics biomarkers in 231 genes, showing significant inter-population pharmacogenome biomarker allele frequency differences.
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Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction
Ruggiero Mango,Fabrizio Clementi,Paola Borgiani,Giovanni B. Forleo,Massimo Federici,Gianmarco Contino,Emiliano Giardina,Luis Garza,Ibrahim E. Fahdi,Renato Lauro,Jawahar L. Mehta,Giuseppe Novelli,F Romeo +12 more
TL;DR: The hypothesis of OLR 1 involvement in atherosclerosis and AMI is validated by defining OLR1 genetic variation by an association study of intragenic SNPs.
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Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype
Fulvia Ceccarelli,Carlo Perricone,Paola Borgiani,Cinzia Ciccacci,Sara Rufini,Enrica Cipriano,Cristiano Alessandri,Francesca Romana Spinelli,Antonio Sili Scavalli,Giuseppe Novelli,Guido Valesini,Fabrizio Conti +11 more
TL;DR: This review will report data currently known about this specific association between specific phenotypes and genetic variants associated with the development of different phenotypes in Systemic Lupus Erythematosus (SLE), except for Lupus Nephritis (LN).
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COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells.
Andrea Latini,Emanuele Agolini,Antonio Novelli,Paola Borgiani,Rosalinda Giannini,Paolo Gravina,Andrea Smarrazzo,Mario Dauri,Massimo Andreoni,Paola Rogliani,Sergio Bernardini,Manuela Helmer-Citterich,Michela Biancolella,Giuseppe Novelli +13 more
TL;DR: Genetic variants in these genes could influence the entry of the SARS-CoV-2 and support the hypothesis that host genetic variability may contribute to the variability in infection susceptibility and severity.