Paola Casolini

TL;DR: Microdialysis was employed to assess extracellular dopamine from medial prefrontal cortex, nucleus accumbens, nucleus caudatus, and acetylcholine from the hippocampus of conscious rats during and after 120 min restraint stress, finding that Adrenalectomized rats responded to stress and liberation in much the same way as intact rats.

TL;DR: A pronounced gender difference in the effects of PRS on anxiety, spatial learning, and a series of neurobiological parameters classically associated with hippocampus-dependent behaviors is uncovered, suggesting that the epigenetic changes in hippocampal neuroplasticity induced by early environmental challenges are critically sex-dependent and that the behavioral outcome may diverge in males and females.

TL;DR: The present results show that the activation of the mesolimbic dopaminergic system induced by aversive stimuli adapts to repeated experiences differently from that produced by pleasurable events, suggesting that aversive and rewarding experiences involve different neural systems.

TL;DR: The results suggest that corticosterone secretion may be one of the mechanisms by which repeated stress amplifies behavioral responses to amphetamine and morphine.

TL;DR: L'axe hypophyso-corticosurrenalien joue un role dans l'augmentation induite par le stress de the liberation de DA et d'Ac choline dans les aires limbiques.