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Paola Frati
Researcher at Sapienza University of Rome
Publications - 195
Citations - 2921
Paola Frati is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Medicine & Health care. The author has an hindex of 23, co-authored 159 publications receiving 1916 citations. Previous affiliations of Paola Frati include American Board of Legal Medicine & University of Sannio.
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Amniotic Fluid Embolism Pathophysiology Suggests the New Diagnostic Armamentarium: β-Tryptase and Complement Fractions C3-C4 Are the Indispensable Working Tools
TL;DR: The pathophysiological mechanism, which underlies AFE, is investigated in order to evaluate the role of immune response in the development of this still enigmatic clinical entity.
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A Controversial Medicolegal Issue: Timing the Onset of Perinatal Hypoxic-Ischemic Brain Injury.
TL;DR: Early-induced molecules driven by hypoxia, as chaperonins HSPs and ORP150, besides common markers for inflammatory responses, have predictive value in timing the onset of neonatal hypoxic-ischemic injury; on the other hand, clinical biomarkers for HII diagnosis, as CK-BB, LDH, S-100beta, and NSE, could be useful to predict outcomes.
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The Troponin-I fast skeletal muscle is reliable marker for the determination of vitality in the suicide hanging.
Alessandra De Matteis,Massimiliano dell’Aquila,Aniello Maiese,Paola Frati,Raffaele La Russa,Giorgio Bolino,Vittorio Fineschi +6 more
TL;DR: The set of results obtained leads us to believe that the use of this antibody (Anti-Troponin I fast skeletal muscle antibody) is very promising to be able to make a certain differential diagnosis between antemortem and postmortem hangings.
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Migrating granulomatous chronic reaction from hyaluronic acid skin filler (Restylane): review and histopathological study with histochemical stainings
TL;DR: Intradermal skin testing before the start of HA filler therapy, and before each subsequent injection, may prevent legal implications for the plastic surgeon.
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Searching for highly sensitive and specific biomarkers for sepsis: State-of-the-art in post-mortem diagnosis of sepsis through immunohistochemical analysis.
Raffaele La Russa,Aniello Maiese,Rocco Valerio Viola,Alessandra De Matteis,Enrica Pinchi,Paola Frati,Vittorio Fineschi +6 more
TL;DR: Some antigens expressed on leukocyte surfaces, endothelial markers and junctions, and soluble factors showed potential reliability in differentiating sepsis cases from controls and further studies are needed to provide a concrete validation for a combination of markers on specific organ samples.