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Paola Perotti
Researcher at University of Turin
Publications - 36
Citations - 743
Paola Perotti is an academic researcher from University of Turin. The author has contributed to research in topics: Adrenocortical carcinoma & Mitotane. The author has an hindex of 14, co-authored 31 publications receiving 513 citations.
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Journal ArticleDOI
Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinoma
Alfredo Berruti,Paola Sperone,Anna Maria Ferrero,Antonina Germano,Arianna Ardito,Adriano Massimiliano Priola,Silvia De Francia,Marco Volante,Fulvia Daffara,Daniele Generali,Sophie Leboulleux,Paola Perotti,Eric Baudin,Mauro Papotti,Massimo Terzolo +14 more
TL;DR: Despite the in vitro activity, sorafenib plus weekly paclitaxel is an inactive salvage treatment in patients with advanced ACC and should not be recommended.
Journal ArticleDOI
Gemcitabine-Based Chemotherapy in Adrenocortical Carcinoma: A Multicenter Study of Efficacy and Predictive Factors
Judith E K Henning,Timo Deutschbein,Barbara Altieri,Barbara Altieri,Sonja Steinhauer,Stefan Kircher,Silviu Sbiera,Vanessa Wild,Wiebke Schlötelburg,Matthias Kroiss,Paola Perotti,Andreas Rosenwald,Alfredo Berruti,Martin Fassnacht,Cristina L Ronchi +14 more
TL;DR: GEM‐based chemotherapy is a well‐tolerated, but modestly active, regimen against advanced ACC and remains an important option for salvage treatment for advanced ACC.
Journal ArticleDOI
Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma
Vasileios Chortis,Vasileios Chortis,Vasileios Chortis,Irina Bancos,Irina Bancos,Thomas Nijman,Lorna C Gilligan,Angela E Taylor,Cristina L Ronchi,Michael W O'Reilly,Michael W O'Reilly,Michael W O'Reilly,Jochen Schreiner,Miriam Asia,Miriam Asia,Anna Riester,Paola Perotti,R. Libe,Marcus Quinkler,Letizia Canu,Isabel Paiva,Maria João Bugalho,Darko Kastelan,M Conall Dennedy,Mark Sherlock,Urszula Ambroziak,Dimitra Vassiliadi,Jérôme Bertherat,Felix Beuschlein,Felix Beuschlein,Martin Fassnacht,Jonathan J Deeks,Michael Biehl,Wiebke Arlt +33 more
TL;DR: Urine steroid metabolomics is a promising tool for postoperative recurrence detection in ACC; availability of a preoperative urine considerably improves the ability to detect ACC recurrence.
Journal ArticleDOI
New perspectives for mitotane treatment of adrenocortical carcinoma.
Soraya Puglisi,Anna Calabrese,Vittoria Basile,Anna Pia,Giuseppe Reimondo,Paola Perotti,Massimo Terzolo +6 more
TL;DR: Mitotane use in an adjuvant setting is off-label, but the recent guidelines endorsed by the European Society of Endocrinology and the European Network for the Study of Adrenal Tumors (ENSAT) recommend it in ACC patients at high risk of recurrence.
Journal ArticleDOI
Decision-making for adrenocortical carcinoma: surgical, systemic, and endocrine management options.
Soraya Puglisi,Paola Perotti,Deborah Cosentini,Elisa Roca,Vittoria Basile,Alfredo Berruti,Massimo Terzolo +6 more
TL;DR: This narrative review addresses diagnostic management, including hormonal, radiological and pathological assessment, and treatment, which should be directed toward both cancer and hormone related problems.